Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"trimethylamine"”.
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Trimethylamine-N-oxide reduction by alteromonas spp.
Trimethylamine-N-oxide (TMAO) is a nitrogenous compound widely distributed in marine fish and invertebrates. It has long been known that TMAO is reduced by bacteria during the post mortem spoilage of iced marine fish, but the mechanism involved and the physiological role have remained unknown. …
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Noncovalent Interactions Involving Microsolvated Networks Of Trimethylamine N-Oxide
… networks with the important osmolyte trimethylamine N-oxide (TMAO). Vibrational spectroscopy, in this case Raman spectroscopy, is used to interpret the effects of noncovalent interactions by solvation with select hydrogen bond donors such as water, methanol, ethanol and ethylene glycol …
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Effects of Trimethylamine N-Oxide on Mouse Embryonic Stem Cell Properties
Trimethylamine N-oxide (TMAO) is a metabolite derived from dietary choline, betaine, and carnitine via intestinal microbiota metabolism. In several recent studies, TMAO has been shown to directly induce inflammation and reactive oxygen species (ROS) generation in numerous cell types, resulting in …
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Factors Contributing to Trimethylamine Generation from Limed and Polymer Conditioned Sludges
Trimethylamine, (CH3)3N, (TMA), odors are often associated with limed and polymer conditioned sludges. This odor has a fishy smell and can be a nuisance to the community surrounding a wastewater treatment plant or land application site. Several factors are thought to determine the amount of TMA …
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Gut Microbiota-Generated Trimethylamine N-Oxide and Cardiometabolic Health in Humans
… microbes metabolize dietary sources to release trimethylamine (TMA). TMA is absorbed and then oxidized by flavin monooxygenase 3 (FMO3) to form trimethylamine N-oxide (TMAO). Elevated TMAO is associated with increased risk of cardiovascular disease and type 2 diabetes; however, the causal nature …
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Gut Microbiota-Generated Trimethylamine-N-oxide and Cardiometabolic Health in Healthy Adults
… diets. Gut microbiota metabolize choline to trimethylamine (TMA) which circulates and is oxidized in the liver to form trimethylamine N-oxide (TMAO). As a result, ingestion of PC or choline could increase levels of TMAO. Preclinical studies indicate a role of TMAO in the development of …
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The Impact of Dietary Fat and Phosphatidylcholine on Increased Trimethylamine-N-oxide Levels
Trimethylamine-N-oxide (TMAO) is an important biomarker of atherosclerosis. TMAO is the product of a hepatic conversion of trimethylamine (TMA). Releasing of TMA moieties is dependent on the adaptation of the gut microbiota to dietary TMA containing substrates such as phosphatidylcholine (PC), …
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Investigating the Influence of Fresh and Aged Garlic Extracts on the Biosynthesis of Trimethylamine N-Oxide
… (CVD) risk, possibly by reducing the risk marker trimethylamine-N-oxide (TMAO). TMAO production in humans is largely influenced by the metabolic activity of the intestinal bacteria on dietary precursors including L-carnitine. Dietary supplementation of bioactive garlic phytochemical allicin has …
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The Elasmobranch-Microbe Relationship: Trimethylamine n-oxide Synthesis, Urea Hydrolysis, and Microbe-Osmolyte Interactions in the Atlantic Stingray, <i>Dasyatis sabina</i>
… of nitrogenous compounds, primarily urea and trimethylamine n¬-oxide (TMAO). Despite the abundance of these plasma osmolytes, it is notable that elasmobranchs appear to lack urease and TMA oxidase (Tmase), enzymes that scavenge urea-nitrogen and synthesize TMAO, respectively. However, urease …
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Studies on the metabolism and excretion of chlorine chloride
… experimentation:</p><p>1. A study of the rate of trimethylamine excretion in the rabbit following oral administration of choline chloride.</p><p>2. A study of the rate of trimethylamine formation while incubating choline chloride with the intestinal contents of rabbits, in an attempt to correlate …
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Structural studies of radical enzymes in bacterial central metabolism
… gasoline and an environmental pollutant. Choline trimethylamine-lyase is used by gut bacteria to degrade choline, producing a byproduct, trimethylamine, which is linked to human diseases. These two enzymes share a common protein fold and also utilize a similar series of steps to initiate chemistry …
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Studies on the Pharmacokinetics of Pinacidil in Healthy Volunteers
… of debrisoquine, the N-oxidation of trimethylamine and the N-oxidation of pinacidil in Caucasian volunteers. Pharmacokinetic analysis was performed by means of computer programs written or amended by myself for use with a Commodore PET microcomputer and by using the nonlinear …
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Applications of a hand-held optoelectronic nose: security screening, medical diagnosis and food inspection
… was explored. We have made attempts to target trimethylamine as a biomarker from vapor or aqueous solution with relevance to point-of-care evaluation of trimethylaminuria (TMAU), using the more accessible cell phone camera as the imaging device. We made use of highly porous sol-gel/plasticized …
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Physiological and phylogenetic studies of marine methanogenic bacteria
… methanol, methylamine, dimethylamine and trimethylamine are substrates for growth; formate and hydrogen are not. Sodium chloride and magnesium concentrations found in seawater are required for optimum growth. RNA homology values indicated that this isolate is a new species. Methanosarcina …
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Synthesis and reactivity of some β-substituted alkylphosphonates
… fragmentation in alkaline conditions to produce trimethylamine, ethylene and metaphosphate was investigated. The results obtained were to give an indication of the susceptibility of (C₆H₃Cl₂)OCH₂CH₂N⁺R₂CH₂CH₂P(OR')O₂⁻ to analogous fragmentation to release 2-(3,4- dichlorophenoxy)ethyldialkylamine …
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Investigating the Role of Various Environment and Process Conditions in Wastewater Sludge Odor Generation
… role in generation of reduced sulfur and trimethylamine (TMA) odor compounds. Results revealed that poor lime dosing can lead to an increase in odors due to biological generation of volatile sulfur compounds (VSCs) during storage. In this study, a belt filter press gave a higher production …
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UNVEILING THE ADVERSE EFFECTS OF POLYSTYRENE NANOPLASTICS IN THE HUMAN-DERIVED HEPG2-OA STEATOTIC-LIKE MODEL, VALIDATING DYSFUNCTIONAL HUMAN-DERIVED SW872 ADIPOCYTE IN VITRO MODELS FOR THE STUDY OF CARDIOMETABOLIC DISEASES, AND ASSESSING TRIMETHYLAMINE N-OXIDE IN A PLIC STUDY SUB-COHORT
Contesto e obiettivi. Le malattie cardiometaboliche (CM) e cardiovascolari (CV) rappresentano attualmente la principale causa di mortalità a livello mondiale. Negli ultimi anni, i progressi della ricerca hanno fatto luce su nuovi potenziali fattori di rischio, coinvolti sia nelle CMD che nelle …
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Post-mortem changes in Nephrops norvegicus muscle : biochemical processes, microbial actions and effects on food quality
… parameters, such as rigor mortis, kvalue, trimethylamine (TMA), ammonia, oxidized lipids, the bacteria load and the pH are generally known to reflect quality. However, none of these parameters is established for N. norvegicus and research is needed to elucidate their importance in this …
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Total electron scattering cross sections of molecules containing H, B, C, N, O, F, Si, P, S, and Cl in the energy range 0.1- 6.0 keV.
… of important biomolecules 2-Butanone Formamide, Trimethylamine, Aniline, Pyrimidine, Anthracene, five nucleic bases (adenine, cytosine, guanine, thymine and uracil) , Phosphoric acid, sugar substitute (Tetrahydrofuran, Furan, Tetrahydropyran, 3-hydroxytetrahydrofuran, D-Glucose, and …
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