Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"trimethyl chitosan"”.
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Preparazione e caratterizzazione di due sistemi carrier: beads a base di chitosano e chitosano/alginato; nanoparticelle di N-trimetilchitosano
Chitosan is a very attractive polysaccharide and it is known to be a favorable pharmaceutical material because of its low toxicity, biodegradability, biocompatibility, mucoadhesivity and natural origin. Therefore it forms an ideal hydrophilic carrier system. In this study we described the …
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Polysaccharide-based nanostructures for growth factor delivery and mesenchymal stem cell activation
… PEMs were constructed using the polycations chitosan and N,N,N -trimethyl chitosan, and the polyanions hyaluronan, chondroitin sulfate, and heparin. An exhaustive spectroscopic study was performed on all of the PEMs pairs to investigate the effects of polyelectrolyte charge density on …
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Control of Inflammation Using Drug Delivery Strategies in in vitro Models
… will detail the adaptation of polysialic acid-N-trimethyl chitosan nanoparticles to be used as delivery vehicles for an NF-κB TFD treatment in in vitro models of rheumatoid arthritis and cystic fibrosis.</p>
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Surface Engineering of Protein Nanoparticles for Intranasal Delivery
… glycol (PEG) and layer-by-layer coating of trimethyl chitosan and CpG oligodeoxynucleotide adjuvants delivered intranasally in murine models and compared to unmodified protein nanoparticles. The localization and biodistribution were observed using non-invasive in vivo imaging and for …
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Polysaccharide-Based Nanocarriers for Improved Drug Delivery
… charged PSA with positively charged N, N, N-trimethyl chitosan (TMC). All three nanocarriers possessed sizes close to 100 nm with low polydispersity (PDI) and high zeta potential values. Literature suggested that these characteristics would allow the nanocarriers to be physiologically stable …
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Studio di formulazione e caratterizzazione di nanoparticelle a base di trimetil chitosano e sodio alginato per il rilascio mirato di farmaci
… positively charged nanoparticles (NPs) based on trimethyl chitosan (TMC) and sodium alginate (SA) as drug delivery systems able to interact with the sialic residues of the mucous membranes. The TMC has been synthesised in our laboratory slightly modifying literature procedure, and characterised …