Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"triiodothyronine"”.
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Some in vivo effects of triiodothyronine on purine nucleotide synthesis
The in vivo effects of triiodothyronine on the synthesis of hepatic purine nucleotides was investigated in sulfaguanidine-fed hypothyroid rats. To prevent the rapid destruction of nucleotides caused by anoxia and ischemia an apparatus was designed to maintain ether anesthesia while providing normal …
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Decreased Triiodothyronine Binding to the Hepatic Nuclear Thyroid Hormone Receptor in the Diabetic Mouse
… mice were grouped together as the controls. Triiodothyronine (T<sub>3</sub>) binding studies at 4°C using nitrocellulose filtration to separate free T<sub>3</sub> from receptor bound T<sub>3</sub> demonstrated an apparent dissociation constant of (1.3 ± 0.8) x 10<sup>-10</sup> M for controls …
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The serum concentrations of anti-Mullerian hormone (AMH), thyroid-stimulating hormone (TSH), free triiodothyronine (fT3) and free thyroxine (fT4) during early pregnancy
The first trimester of pregnancy is a dynamic time of change involving the implantation and development of the fetus, together with a wide range of related endocrine changes arising from the ovary and feto-placental unit, as well as other changes in maternal and fetal physiology. The present …
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Changes in Thyroid Function Associated With Pregnancy in Golden Hamsters
Thyroxine (T₄) and triiodothyronine (T₃) utilization rates were calculated to determine the changes in thyroid function during pregnancy in the hamster, (Mesocricetus auratus). Turnover rates were calculated via the plasma disappearance technique using ¹²⁵I-labeled hormones. Serum T₄ and T₃ were …
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The laboratory assessment of thyroid function with special reference to the importance of thyroid abnormality in psychiatric disease
… in vitro assays for serum thyroxine (T+), triiodothyronine uptake (T3U), triiodothyronine (13) and thyroidstimulating hormone (TSH) , together with the development and evaluation of both thyroxine binding globulin (TBG) and thyroxine binding prealbumin (TBPA) assays. For comparison, both …
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Studies in the biosynthesis of the hormones of the thyroid gland.
… (MIT) and the pathways of synthesis of triiodothyronine (T3 ) and thyroxine (T4 ).
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Evaluation of the effects of clomipramine on the canine hypothalamic-pituitary-thyroid axis
… (TSH), total thyroxine (T4), total 3,5,3' triiodothyronine (T3), free thyroxine (fT4), and 3,3',5' triiodothyronine (reverse T3; rT3) concentrations were measured on selected days. Thyrotropin-releasing hormone (TRH) response tests were performed concurrently. Repeated measures analysis of …
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The Alteration of Thyroid Hormone Level during Liver Transplantation
"배경: 비갑상선질환 증후군은 triiodothyronine (T3)치가 단독으로 저하되어 있거나 T3 와 tyroxine (T4)치가 같이 저하되어있는 것이 특징이다. 이는 기아, 패혈증, 심근경색, 심장 혹은 비 심장수술 환자에서 관찰 되며, 어떤 심한 질병과도 동반될 수 있다. 원인은 명확히 알려져 있지 않으나, interleukine-6 (IL-6), tumor necrosis factor-a (TNF-a)와 같은 cytokines가 요소 중 하나로 제시되고 있다. 간이식수술은 cytokines의 급격한 변화를 겪는 …
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Extrathyroidal thyroid hormone activation in ring doves
… in the presence of abundant substrate, reverse triiodothyronine (rT3), cofactor (dithiothreitol) and trace amounts of I¹²⁵-rT3. 5’D activity was measured as I¹²⁵ released from the labelled rT3 during the assay incubation time. The 5’D assay was validated for all ages studied to assure that the …
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Α-ΦΕΤΟΠΡΩΤΕΙΝΗ ΚΑΙ ΣΥΓΓΕΝΗΣ ΥΠΟΘΥΡΕΟΕΙΔΙΣΜΟΣ
… MONTH. DURING REEXAMINATIONA-FP, THYROXINE (T4), TRIIODOTHYRONINE (T3) AND THYROTROPIN (TSH) HORMONES WERE MEASURED IN SERUM AND A CLINICAL EXAMINATION AS WELL AS BONE AGE ESTIMATION BY SENECAL METHOD WAS PERFORMED. BY THE AGE OF ONE YEAR THE GRIFFITHS DEVELOPMENTAL TEST WAS GIVEN TO CH INFANTS …
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The influence of diet on growth rate, thyroid hormone output, and thermoregulation in laboratory white rats
… levels of thyroxine (T{dollar}\sb4{dollar}), triiodothyronine (T{dollar}\sb3{dollar}), free thyroxine index (FT{dollar}\sb4{dollar}), and thyroid stimulating hormone (TSH) were measured. Food intake expressed per g BW was highest in the LP (5% protein) diet group, but body weight gain was the …
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The role of thyroid hormones in placental development and the importance of the thyroid hormone transporter MCT8
… IUGR compared with normal pregnancies. In vitro, triiodothyronine (T\(_3\)) decreased survival and increased apoptosis of IUGR compared with normal cytotrophoblasts, which was associated with increased MCT8 expression. In normal cytotrophoblasts, MCT8 upregulation decreased survival, whilst MCT8 …
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Hepatic 5'deiodinase activity of Japanese quail using reverse-T2 as substrate: assay validation, characterization, and developmental studies
Using reverse-triiodothyronine, rT3, as substrate, an in vitro 5'deiodinase (5'0) assay was validated for adult Japanese quail, by defining conditions under which activity is proportional to enzyme (protein) concentration and is linear with incubation time. Activity was measured as the release of …
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Seasonal Energetics of the Cotton Rat (Sigmon Hispidus) From Southwest Missouri
… (T₄) levels (June, 1988 through April, 1989) and triiodothyronine (T₃) serum levels (February, 1989 through January 1990) were analyzed. Oxygen consumption data were measured at temperatures between 5°-36°C and NST was elicited by a subcutaneous injection of norepinephrine. Oxygen consumption data …
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In vitro milk protein secretion by explants of Holstein bull mammary tissue from two different genetic lines
… medium (St), which was further supplemented with triiodothyronine, estradiol 17-B, hydrocortisone, and bovine prolactin (PRL). Explants in duplicate multi-well culture dishes were incubated in the presence of 3H-Iabeled amino acids or 3H-Iabeled thymidine. Measurements made included: casein in …
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Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease
… we examined the effect of the thyroid hormone triiodothyronine (T3) and the agonist of the thyroid hormone receptor β isoform (TRβ), GC-1, on fatty liver and steatohepatitis induced in rodents by a choline-deficient, methionine-restricted (CMD) diet. Male Fischer rats fed the CMD diet for 1 …
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GROWTH PATTERNS AND SIZE-GROUP INTERACTIONS IN HATCHERY-REARED AGE-0 LAKE STURGEON
… and levels of free plasma thyroid hormones triiodothyronine (T<sub>3</sub>) and thyroxine (T<sub>4</sub>). A single family of lake sturgeon (one male/female cross) was raised in the Northern Michigan University Aquatics laboratory for one year. Growth of the sturgeon was determined both as …
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Preneoplastic hepatocyte hypothyroidism underlies hepatocellular carcinoma progression
… are mediated by the thyroid hormone 3,5,3’-L-triiodothyronine (T3) nuclear receptors (THRs), which act as transcription factors. THRs have also been implicated in tumorigenesis, although it is unclear whether they act as oncogenes or tumor suppressors. Here, experiments were performed to …
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Regulation of LKB1-STRAD-MO25 Complex Expression and Activation of AMPK in Skeletal Muscle by Thyroid Hormone
… in rats given 3 mg of thyroxine and 1 mg of triiodothyronine per kilogram chow for 4 weeks, and in rats given 0.01% propylthiouracil (PTU) in drinking water for 4 weeks. The relative expression of LKB1, MO25, and STRAD, as well as PGC-1α, increased in the soleus of thyroid hormone treated …
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