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Showing 1 to 20 of 26 for “"trigeminal nerve"”.
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Non-invasive measurement of trigeminal nerve somatosensory evoked potentials
… common yet enigmatic to substantiate clinically. Trigeminal somatosensory evoked potentials (TSEPs) were posited as an indicator of trigeminal nerve conduction damage resulting from whiplash. Alternating polarity square-wave current stimuli were applied transcutaneously in the facial region. 379 …
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Inhibition of Retinoic Acid Receptors Results in Defasciculation of the Trigeminal Nerve in Xenopus laevis
… yet surprisingly little is known about how the nerves are guided to their targets. The study of the development of these nerves has important implications for our understanding of craniofacial anomalies and possible treatments for both injury and genetic disorders of nerve development such as …
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THE ROAD LESS TAKEN: CHARACTERIZING THE TRIGEMINAL NERVE ROUTE OF NEUROINVASION BY RESPIRATORY SARS-COV-2
… in consciousness. Although the olfactory nerve is widely accepted as the primary route of neuroinvasion by which the etiological agent SARS-CoV-2 invades the brain, the trigeminal nerve may serve as an additional, yet often overlooked, neuroinvasive route. We initially conducted a pilot …
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Topological organization of the trigeminal system in the lamprey and restoration following axonal regeneration
… existence of a topological organization of the trigeminal system in the lamprey. The purpose of the current study was two-fold: (1) confirm the topological organization of the trigeminal system in normal animals; and (2) determine if this organization is restored following trigeminal nerve …
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Accelerating development of treatments for trigeminal neuralgia using intranasal delivery and a novel behavioral screening device for rats.
… to treat because of poor targeting to the trigeminal, orofacial and brain structures involved. Intranasal administration targets these structures while minimizing systemic exposure and side effects. Lidocaine was intranasally administered to rats, and the trigeminal nerve and …
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Identifying Potential Agonists Of TRPA1 Using A Heterologous Expression System And Transgenic Mice
Chemical irritants stimulate the trigeminal nerve through many different receptor proteins, including TRP channels. TRPA1, a highly conserved TRP channel, is known to be activated by over ninety compounds. As TRPA1 is promiscuous in nature, it was considered a likely receptor for stimuli activating …
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Effects of Single and Dual Orexin Receptor Antagonists on Trigeminal Nociception
… perception. This disorder is mediated by the trigeminal nerve, which provides sensory innervation to the face, scalp, and meninges. Migraine pain is conveyed to the brain via the trigeminothalamic tract, which relays nociceptive signaling from primary nociceptors to the hypothalamus. Orexins …
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Anatomical Complications Related to Dental Implant Surgery
… artery and its branches, maxillary division of trigeminal nerve (CN V2), mandibular division of trigeminal nerve (CN V3), and several muscles associated with the oral cavity. Cadaveric photographs and cone beam computed tomography scans (CBCT) are used to help demonstrate the pathway of arteries …
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Quantitative Studies of the Mesencephalic Nucleus of the Trigeminus
… the motor and sensory branches of the mandibular nerve. | The nucleus is composed of two or more distinct types of cells that participate in either a relay or sensory perception function. These cells give off at least one process which courses with the processes of the other mesencephalic cells to …
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Effects of REM Sleep Deprivation on Trigeminal Nerves: Increased Thermal Sensitivity
… joint disorder. Sensitization and activation of trigeminal nerves, which provide sensory innervation to much of the head and face and mediate pain and inflammation, are implicated in the underlying pathology of these diseases. I hypothesized that sleep deprivation would cause sensitization of …
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Secondary Traumatic Stress Promotes Central Sensitization of the Trigeminal System
… peripheral and central sensitization of trigeminal nociceptive nerves. Since migraine is often comorbid with temporomandibular joint disorder and inflammatory bowel disease, it is associated with significant social and economic burdens. Primary traumatic stress is a significant risk …
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THE RESPIRATORY RESPONSE OF TRPV1 KNOCKOUT MICE TO TRIGEMINAL IRRITANTS
The trigeminal nerve is composed of polymodal neurons which innervate the nasal cavity, nasopharynx, oral cavity and cornea. Trigeminal nociceptive fibers are stimulated by a wide variety of chemical irritants. However, the mechanism of stimulation is known for only a few compounds. TRPV1 channels, …
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Multimedia Educational Resource of the Temporomandibular Joint for Dental Students
… is supplied by the mandibular division of the trigeminal nerve (V3). This is a very compact space with various vessels, ligaments and muscles. The TMJ is a location of unique movements and structures which are often difficult to visualize for dental students. The purpose of this presentation …
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The role of serotonergic afferents in receptive field organization and response properties of cells in rat trigeminal subnucleus interpolaris
Damage to peripheral nerves can cause extensive functional reorganization of the adult mammalian nervous system. In fact, studies in non-human adult mammals have shown somatotopic reorganization as well as changes in receptive field properties throughout the somatosensory neuraxis following damage …
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Impact of Acoustic and Tactile Multi-Modal Stimulation on Objective and Subjective Measures of Permanent Intractable Tinnitus: A Prospective Research Study
… structures and input from the branches of the trigeminal nerve and that stimulation of these nerves can qualitatively and quantitatively influence tinnitus perception. Studies have shown that using Transcutaneous Electrical Nerve Stimulation (TENS) to stimulate the C2 dermatome can have a …
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IDENTIFICATION OF KEY MOLECULES IN PLACODE-DERIVED NEURONS THAT COORDINATE CHICK TRIGEMINAL GANGLIOGENESIS
The trigeminal nerve is the largest of the cranial nerves, possessing three main branches (ophthalmic, maxillary, and mandibular) and relaying sensations of pain, touch, and temperature from the face and head to the brain. Cell bodies of this nerve are positioned in the trigeminal ganglion, which …
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The use of the Fos technique to investigate the physiology and pharmacology of trigeminovascular sensation
… largely unknown, but what is known is that the trigeminal nerve plays a central role in relaying nociceptive information from the " pain-sensitive" intracranial/extracerebral blood vessels to the central nervous system (CNS). This pathway is referred to as the " trigeminovascular …
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Clinical symptoms and volumetric radiological responses of acoustic neuroma patients, treated with hypo-fractionated image guided radiotherapy (IGRT) at Groote Schuur hospital between 2013 and 2016
… preservation rate was 67%. No new facial or trigeminal nerve symptoms were noted. Radiologists correctly reported tumour growth in 100% of tumours that grew, and specificity was 77.3% in those that were stable. Conclusion: This is the first local study in hypofractionated SRT using photons. …
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Olfactory Ensheathing Cell Development: A Transcriptome Profiling Approach
… cells (OECs), the glia of the olfactory nerve, are promising candidates for patient-specific cell-mediated repair of both peripheral nerves and the spinal cord. The recent discovery that OECs originate from the neural crest, rather than the olfactory epithelium as previously thought, …
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Nanocarriers for nose-to-brain delivery: a novel strategy for the treatment of CNS disorders
… to the brain through the olfactory epithelium by trigeminal nerve systems and olfactory nerve pathways thereby bypassing the BBB. The incorporation of drugs into nanoparticles (NPs) might be a promising approach to improve the amount of pharmaceuticals delivered to the CNS. The goal of my PhD …
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