Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"treatment prediction"”.
-
Exploiting Structure Information for Network Dissimilarity Characterization - Application to Disease Network Analysis and Treatment Prediction
… to multiple ways cancer initiates and develops treatment resistance. Models that represent these differences and the underlying molecular mechanism in cancer enhance the possibility in characterizing and in turn treating cancer successfully. We introduce novel graph-based methods for exploiting …
-
Translational Neuroimaging of Emotion Processes in Posttraumatic Stress Disorder and Depression
… Similarly, neurobehavioral signatures of treatment response prediction may vary based on the task or context probed. In these studies, we examined how neuroimaging of emotion processes may shed light on mechanisms underlying symptom heterogeneity in PTSD (Study 1) and how similar …
-
Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer
Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. The …
-
Non-linearity and Dispersion Effects in Tissue Impedance during Application of High Frequency Electroporation-Inducing Pulsed Electric Fields
… muscle contractions associated with IRE-based treatments. Furthermore, H-FIRE exhibits the potential to improve lesion predictability in homogeneous and heterogeneous tissue masses. Therapeutic IRE and H-FIRE utilize source and sink electrodes inserted into or around the tumor to deliver the …
-
Short interval change in hepatitis C hypervariable region 1 in chronic infection. Are there treatment windows in the envelope?
… liver transplantation in the United States. Dual treatment with pegylated interferon and ribavirin has until 2010 been the mainstay of treatment. The emergence of newer agents with direct activity against specific virus proteins has revolutionised HCV treatment but, the high cost of these …
-
Prognostic and treatment predictive factors for radio- and chemotherapy resistance in breast cancer patients- a step towards personlized medicine
… form among women in the Western world. Although treatment has improved during the last decades, there is still a significant proportion of the patients who are not cured. To further improve clinical outcome we need new treatment strategies, new prognostic markers, and new treatment predictive …
-
Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer.
One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of …
-
A cohort study of sex differences and prognostic biomarkers in colorectal cancer
… and to help select patients for adjuvant treatment. The aim of this thesis was to investigate the associations of a series of putative biomarkers with survival, treatment response and clinicopathological factors in a large cohort of incident CRC, with special attention to sex differences. …
-
Towards a data-driven personalised approach to gestational diabetes care
… are reviewed at clinical appointments, where treatment may be escalated. Current care in Scotland is time-consuming and does not utilise the potential of risk-stratification and digital tools. This thesis proposes an alternative method of care that does so by risk stratifying women with GDM …