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Showing 1 to 2 of 2 for “"transsynaptic tracing"”.

  1. Investigating circuit and spatial heterogeneity of human brain tumors with patient-derived organoid models

    … virus and herpes simplex virus (HSV)-based transsynaptic tracing techniques in the rodent brain to define a whole-brain connectome of GBM-projecting neurons. We found that, remarkably, GBM receives inputs from all over the brain and are innervated by diverse neural subtypes, such as …

    penn Repository record for Investigating circuit and spatial heterogeneity of human brain tumors with patient-derived organoid models (opens in a new tab)

  2. Functional Labeling of Individualized Post-Synaptic Neurons using Optogenetics and trans-Tango

    Neural circuitry, or how neurons connect across brain regions to form functional units, is the fundamental basis of all brain processing and behavior. There are several neural circuit analysis tools available across different model organisms, but currently the field lacks a comprehensive method …

    vt Repository record for Functional Labeling of Individualized Post-Synaptic Neurons using Optogenetics and trans-Tango (opens in a new tab)