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Showing 1 to 20 of 26 for “"transport kinetics"”.
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Photoinitiated proton-coupled electron transfer and radical transport kinetics in class la ribonucleotide reductase
… underpinning key processes such as radical transport, energy transduction, and enzymatic substrate activation. Ribonucleotide reductases (RNRs) rely on PCET to mediate the rate-limiting step in the synthesis of DNA precursors. E. coli class Ia RNR consists of two dimeric subunits: [alpha]₂ …
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Initial oxidation of zirconium : chemistry, atomic structure, transport and growth kinetics
… of the initial oxide on zirconium and the oxygen transport kinetics through this oxide under electric field. This goal is important for enabling more accurate zirconium oxidation models, for example for nuclear reactor materials, as well as for assessing the mechanisms that govern the performance …
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Characterization of pathogen transport in overland flow
Overland transport kinetics of pathogens are controlled, in large part, by soil and vegetation. With an increasing number of concentrated animal operations, there is becoming a greater need to dispose of a vast amount of manure in a single, localized area. Animal manure contains a substantial …
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The role of Huntingtin in fast axonal transport
… the putative function of Htt in fast axonal transport, we characterized the co-localization of the Drosophila Htt homolog tagged with mRFP (dHtt-RFP), and the alterations in axonal transport kinetics associated with a dhtt null. We find that dHtt co-localizes with a subset of cargos including …
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Characterization of the Genes Involved in Biosynthesis and Transport of Schizokinen, a Siderophore Produced by <em>Rhizobium leguminosarum</em> IARI 917.
… ferric ions, bind with high affinity, and transport it into the cell via multicomponent transport systems. <em>Rhizobia</em> are soil dwelling organisms that form symbiotic relationships with host plants and fix atmospheric nitrogen, while the bacteria receive nutrients. <em>R. …
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Adsorption, encapsulated solute leakage and microflow of giant vesicles during anhydrobiotic preservation in trehalose solutions
… little attention has been paid to the effect of transport kinetics on preservation success. Further, although cells are typically dried in carbohydrate solutions on a solid support, there are few studies on the role played by the support. This work seeks to help remedy such deficiencies. First, …
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Quantitative Studies of Intracellular Trafficking of Two Classes of Resident Golgi Apparatus Proteins
… initial project, the anterograde and retrograde transport kinetics of this Golgi protein were determined and used to develop a compartmental model for pH sensitive trafficking in the bypass pathway. The spatial Golgi distribution of the protein during retrograde transport to the Golgi following …
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Molecular Size and Charge Effects on Nucleocytoplasmic Transport Studied By Single-Molecule Microscopy
… machinery for bidirectional nucleocytoplasmic transport. The selective barrier, which is formed by the natively unfolded phenylalanine-glycine (FG)-nucleoporins (Nups), in the NPC allows for two transport modes: passive diffusion of small signal-independent molecules (< 20-40 kDa) and …
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Folate transport and drug resistance in the African Trypanosome
… in African trypanosomes with a specific focus on transport mechanisms. A media deficient in folate and thymidine was established which enabled the assessment of their modulation on antifolate in vitro potencies and also screen a small set of antifolate compounds. The phenomenon of …
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Predictive Disintegration Process Modelling of Immediate Release Tablets Using Terahertz Technology
… front during tablet hydration, capturing liquid transport kinetics and matrix evolution insights. To capture disintegration realistically, including matrix erosion often ignored in constrained setups, a novel open immersion cell was developed for THz liquid transport profiling. This uniquely …
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The durability of adhesive joints: an engineering study
… In the rubbery state, it is assumed that the transport kinetics is governed by the constant redistribution of the free volume, caused by the segmental motions of the polymeric chains. An expression for the diffusion coefficient is inferred from the temperature, strain and penetrant …
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Quantification of membrane transport rates using optofluidics
The transport of ions and small molecules across membranes is a ubiquitous process in biological systems. Effective studies of membrane transport phenomena require suitable model membrane systems, efficient methods to quantify transport kinetics and a robust theoretical framework to derive …
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Defect equilibria and electrode kinetics in Prx̳Ce1̳-̳x̳O2̳-̳[̳d̳e̳l̳t̳a̳]̳ mixed conducting thin films : an in-situ optical and electrochemical investigation
… understanding of oxygen defect equilibria and transport kinetics in oxides is essential for achieving enhanced performance and longevity in many oxide-based practical applications. The ability to diagnose a material's behavior in a thin film structure under operating conditions (in operando), …
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Novel Plasmonic Nanostructures for Applications in Sensing, Imaging, and Controlled Release
… imaging by photoacoustic: PA) tomography. The transport kinetics of Au nanocages in a lymphatic system was evaluated by PA imaging on the axillary region of a rat. Several experimental parameters, including the injection concentration, particle size, and surface charge were systematically …
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Molecular mechanisms of gating and selectivity in transport channels
Transport channels and pores are of fundamental importance for translocation of molecules across the otherwise-impermeable biological membrane. As a conduit for the passage of material, specific membrane channels must accomplish the task of selective transport of molecules, while preventing …
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Gas Separation Using Nanoporous Single-Layer Graphene Membranes
… pores to larger pores. I formulate the transport kinetics associated with the direct impingement from the bulk and with the surface diffusion from the adsorption layer on graphene, and then combine them to predict the overall gas permeation rate using a reaction network model. Last, I …
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Quantitative Carrier Transport in Quantum Dot Photovoltaic Solar Cells from Novel Photocarrier Radiometry and Lock-in Carrierography
… due to the not-well-understood carrier transport mechanisms and the lack of effective characterization techniques. Addressing these issues, carrier transport kinetics in CQD systems were studied to develop high-frequency dynamic testing and/or large-area quantitative imaging techniques: …
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Amorphous calcium phosphate nanocomplexes in dental film formulations
… mode with Fickian, non-Fickian and super case II transport kinetics depending on the type of ACP and the grade of HPMC used. The effect of a biofilm generated on the tooth surface to make the substrate more hydrophobic was examined. The adhesion of 15% (w/v) HPMC-E10M hydrogel to enamel slabs was …
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Functional characterisation of the human mitochondrial ATP-Mg/Pi carriers and their disease-causing variants
… carrier domain, which catalyses substrate transport. In the proposed “locking-pin” mechanism, the amphipathic helix is bound to the regulatory domain in the presence of calcium, whereas it is bound to the carrier domain in the absence of calcium. There are four different human APC …
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Effects of Chronic High Sucrose With Dietary or Drinking Inclusion on the Electrogenic Glucose Absorption in the Intestinal Tract of Mice (Mus musculus)
… intestinal electrogenic sodium dependent glucose transport, the first portal of entry for glucose, is unknown. Here female C57bl/6 mice fed a normal standard chow diet, and 20% sucrose in the drinking water for 8 months, or 35% sucrose inclusion in the diet for 12 months were assessed. The …
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