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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 122 for “"transmembrane protein"”.

  1. Identification and characterization of layilin, a talin-binding transmembrane protein

    Borowsky, Mark Lee, 1966-Massachusetts Institute of Technology1999

    Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.

    mit Repository record

  2. NUCLEAR ENVELOPE TRANSMEMBRANE PROTEIN DISTRIBUTION AND TRANSPORT STUDIED BY SINGLE-MOLECULE MICROSCOPY

    Mudumbi, Krishna ChaitanyaTemple University. Libraries2018

    … nucleus and cytoplasm by forming a barrier. NE transmembrane proteins (NETs) embedded in either the outer nuclear membrane (ONM) or the inner nuclear membrane (INM) play crucial roles in both nuclear structure and functions, including: genome architecture, epigenetics, transcription, splicing, …

    temple Repository record

  3. CHARACTERIZATION OF TRANSMEMBRANE PROTEIN 35 EXPRESSION: CONSIDERATIONS OF SEX AND OVARIAN HORMONES

    Vanderplow, Amanda M2018

    <p>The recently discovered novel neuropeptide transmembrane protein 35 (TMEM35), is believed to modulate chemical signaling within the nervous system. Notably, the TMEM35 protein is detectable in humans, non-human primates and rodents, suggesting a conserved and critical function. Despite this, the …

    nmu Repository record

  4. Functional studies on the transmembrane protein encoded by the TM20 gene in maize

    Jahrmann, Torben2012

    … worden, das für eine neue Klasse von Transmembranproteinen kodiert. Die Mutation blockiert die Entwicklung von Embryo und Endosperm in der Transitionsphase. Die vohergesagte Proteinstruktur zeichnet sich durch zwanzig hydrophobe Segmente aus, die in f ünf Gruppen von je vier Segmenten …

    goettingen Repository record

  5. Modification of Lipid Microenvironments on Solid Support Structures for Use in Transmembrane Protein Assays

    Houlihan, William J2019

    <p>Gamma-Secretase (γ-secretase) is a transmembrane protease of increasing interest, which has been shown to have significant connections to both cancer and Alzheimer’s disease. γ-secretase cleaves both Notch-1, a transmembrane signaling protein, and Amyloid precursor protein (APP), a transmembrane …

    cuny Repository record

  6. Self assembled transmembrane protein polymer conjugates for the generation of nano thin membranes and micro compartments

    Charan, HimanshuUniversität Potsdam

    … stimuli responsive membranes with an embedded transmembrane protein to act as the pore. The membranes were formed by crosslinking of transmembrane protein polymer conjugates. The conjugates were self assembled on air water interface and the polymer chains crosslinked using a UV crosslinkable …

    potsdam-diss Repository record

  7. The functions and the mechanism of action of the ephrin-B1 transmembrane protein in human malignant T cells.

    Jiang, GuangpingFaculty of Graduate Studies and Research, University of Regina2008

    regina Repository record

  8. Characterization of a Seven-Transmembrane Protein and a Putative Ligand with Respect to Behavior and Iron Uptake in Tetrahymena thermophila

    Zou, DianxiongState University of New York at Buffalo2019

    Ph.D.

    buffalo Repository record

  9. THE ROLE OF NIEMANN-PICK C1-LIKE 1 (NPC1L1) PROTEIN IN CHOLESTEROL TRANSPORT AND METABOLIC DISEASES

    Jia, LinWake Forest University2010

    Niemann-Pick C1-Like 1 (NPC1L1) is a polytopic transmembrane protein critical for intestinal absorption of dietary and biliary cholesterol. Ezetimibe, by inhibiting NPC1L1 function, is widely used to lower blood cholesterol in humans. Recently, NPC1L1 deficiency or ezetimibe treatment has been …

    wfu Repository record

  10. Investigating the parameters affecting the sensitivity of a protein nanopore sensor

    Ghahari Larimi, Motahareh

    … to design a nanopore sensor for sampling peptide-protein and protein- protein interaction. To pave the way for designing a high-throughput wearable nanopore sensor, we will investigate a few of the parameters that can potentially influence the sensitivity and reproducibility of a sensor and …

    syracuse-diss Repository record

  11. Synthetic Strategies and Design of Highly Luminescent Cholinomimetic Quantum Dots

    McAtee, Maria L.University of Toledo2012

    <p>The high affinity choline uptake transmembrane protein (CHT) is an important part of the cholinergic transport cycle and yet the structure of this transmembrane protein has still not been determined. The concentration and functionality of choline has been observed to be depleted in …

    ohiolink Repository record

  12. HUMAN CLCA2 IS A P53-DEPENDENT ZINC METALLOPROTEASE AND ITS INTERACTION WITH EVA1 MAINTAINS DIFFERENTIATION OF HUMAN MAMMARY EPITHELIAL CELLS

    Ramena, Grace Theresa Nicholas2017

    CLCA2 is a p53-inducible transmembrane protein that is frequently downregulated in breast cancer. CLCA2 is a 943 amino acid type I transmembrane protein that is cleaved near amino acid 700 to produce a diffusible 100kD product. The N-terminus contains a hydrolase-like domain with well-conserved …

    siu-theses Repository record

  13. Mechanisms Of Presynaptic CaV2 Calcium Channel Localization In Caenorhabditis Elegans

    Saheki, Yasunori

    … CALF-1 is a neuronal-specific one-pass transmembrane protein that resides in the endoplasmic reticulum, and is required for endoplasmic reticulum exit of UNC-2. Structure-function analysis revealed that the transmembrane domain and the cytosolic arginine-based basic motifs are important …

    rockefeller Repository record

  14. Interactions between Human Two-pore Channels and Nonaspanin Proteins

    SUN, LEISHENG2016

    … Here I find that TM9SF1, a nine-spanning transmembrane protein and human two-pore channels (TPCs) regulate cell autophagy. More importantly, TM9SF1 and TPCs are found in endolysosomal system, and among all TM9SF family, only TM9SF1 interacts with TPC2 structurally, which suggests that …

    umn Repository record

  15. Cloning and Sequencing of Bovine Na+/K= Atpase α-1 Sub-Unit

    Aakula, Srikanth

    … also called the Na+ pump, is a crucial transmembrane protein. By transporting water and ions from and through the cornea into the aqueous humor, it is responsible for maintenance of structural integrity, corneal hydration and thereby transparency of the cornea. The Na+ pump is …

    wku-diss Repository record

  16. Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis

    Lee, Hyeseung

    … molecular and genomic approach, we identify the transmembrane protein 2 (TMEM2) gene as a direct transcriptional target of SOX4. TMEM2 is transcriptionally activated by SOX4 in both breast cancer and lung adenocarcinoma cells and mediates pro-invasive and pro-migratory effects of SOX4. TMEM2, …

    rockefeller Repository record

  17. The Role of Membrane Lipid Composition on Sarco(endo)plasmic Reticulum Calcium ATPase Function in Rat Soleus Muscle

    Trojanowski, Natalie S.Brock University2015

    … reticulum calcium ATPase (SERCA) is a transmembrane protein whose function is regulated by its immediate lipid environment (annulus). The composition of the annulus is currently unknown or it’s susceptibility to a high saturated fat diet (HSFD). Furthermore it is uncertain if HSFD can …

    brock Repository record

  18. Microscopic and Spectroscopic Investigation Of: I. Copper-Additive Systems in Electroplating Bath. II. Supported Phospholipid Bilayer Systems

    Feng, Zengqi VivianUniversity of Illinois at Urbana-Champaign2015

    … the support and the bilayer. Addition of the transmembrane protein gramicidin A or construction of a highly defected gel phase results in elimination of this decoupling and removal of the secondary phase transition.

    uiuc Repository record

  19. New tools for the discovery of pigment gene function

    Adelmann, Charles H.Massachusetts Institute of Technology2021

    … in human pigmentation. Many of these encode proteins that localize to the melanosome, the lysosome-related organelle that synthesizes pigment, but have unclear functions. Here, we describe the MelanoIP method for rapidly isolating melanosomes and profiling their labile metabolite contents. We …

    mit Repository record

  20. Molecular Basis of Mechanosensitivity

    del Marmol, Josefina Ines

    … 2 potential candidates including one novel protein subsequently confirmed to modify the behavior of Piezo1 in vitro. This protein, Plp2, is a small transmembrane protein of undescribed function that amplifies the magnitude and slows down the kinetics of Piezo1 in heterologous expression. The …

    rockefeller Repository record

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