Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 23 for “"transmembrane potential"”.
-
EFFECT OF CRYOPROTECTANT EQUILIBRATION ON TRANSMEMBRANE POTENTIAL OF BOVINE OOCYTES
… osmotically induced volume perturbation on the transmembrane potential of bovine oocytes. The aim of this study was to evaluate and examine the difference in putative effects of non-permeating (PBS) and permeating (10% EG) solutions and to explore the association between osmotically induced …
-
Asymmetrical transmembrane potential in intracellular organelles of adrenal chromaffin cells exposed to nanosecond electric pulses
… literature, there is no evidence of asymmetrical Transmembrane Potential (TMP) distribution in the intracellular membranes. However, these models do not include a realistic number of intracellular organelles. The goal of this research was to construct a more realistic cell model that incorporates …
-
Dynamic Electroporation Modelling
… electric field waveforms have on the induced transmembrane potential of the cell and by consequence the electropermeabilization of the cell membrane in terms of pore density or the fraction of the cell area that the pores occupy. Conventional biotechnology processes of electroporation make use …
-
Pulse electric field exposure effect on morphological properties of HeLa cells
… are to prove the existence of the effect on transmembrane potential changes when subjected exposed to PEF strength. This result can be seen clearly when both method showed the existence of changes effects on transmembrane potential. Therefore, this study continues by identifying an …
-
Modeling And Detection Of Uterine Contractions Using Magnetomyography
… and, as a consequence, on modeling the transmembrane potential evolution as a function of time. In this work, we propose an electromagnetic modeling approach taking into account electrophysiological and anatomical knowledge jointly at the cellular, tissue, and organ levels. Our model …
-
Modulation of the Magnetic Properties of Aqueous Metal Ions and the Bioelectrodynamic Effects on Cancerous and Noncancerous Cells
… cell cycle arrest, hyperpolarization of transmembrane potential and apoptosis of cancerous cells while not causing a growth inhibition, cell cycle arrest or apoptosis of the noncancerous cell lines. Microarray and RT-qPCR show the cancerous cells headed to apoptosis by the unfolded …
-
Optical method of recording electrical activity in isolated rabbit hearts
… This optical technique generates recordings of transmembrane potential from excitable myocardial tissue, and remain free from stimulus artifacts that accompany electro stimulation and hinder all standard electrode recording methods during the application of high-voltage electrical shocks. The …
-
Passive Electrical Properties of Horizontal Cells in the Retina of the Turtle, Pseudemys Scripta Elegans
… was applied to the passive relaxation of the transmembrane potential in response to 20 ms pulses of current in luminosity-type and chromaticity-type horizontal cells. The time course of the relaxation was described by the sum of two exponentially decaying processes. The passive responses were …
-
Human telomerase reverse transcriptase (hTERT) overexpression modulates intracellular redox balance and protects cancer cells from apoptotic cell death
… translocation of Bax, the drop in mitochondrial transmembrane potential, the release of cytochrome C to the cytosol, and cell death. Taken together, these data demonstrate a hitherto undefined role of hTERT in alleviating cellular ROS levels by way of potentiating the cellular anti-oxidant …
-
The Relationship between Ephaptic Coupling and Excitability in Ventricular Myocardium
… on the subthreshold current required to raise transmembrane potential to the activation threshold and subsequent recruitment of voltage gated sodium channels to trigger an action potential. Conduction in cardiomyocytes is dependent on the robustness and speed of action potential propagating …
-
Pacemaking Neurons in the study of Parkinson’s Disease
… model explicitly describes the dynamics of the transmembrane potential with changes in the levels of important cations. The model is veriVed for two major observations in literature regarding its response in the presence of channel blockers. The model is analysed for parameter bifurcation and …
-
Avaliação do potencial antileucêmico de adutos aromáticos de morita-baylis-hillman.
… microscope. The cell cycle and mitochondrial transmembrane potential analyzes were measured using the flow cytometry technique. Using the MTT assay, the compound A2CN showed greater potency against the strain HL - 60 (IC 50 = 22 μM) and MOLT - 4 (21 μM ) than in PBMC (71 μM) after 24 hours of …
-
Interplay of Brain Derived Neurotrophic Factor and Protein Kinase A in Modulating Mitochondrial Structure and Function in Brain Homeostasis and Disease
… and glycolysis) and increased the transmembrane potential of mitochondria; processes that required activation of trkβ. Furthermore, BDNF-mediated enhancement of mitochondrially-localized PKA was associated with increased resistance of primary cortical neurons against …
-
An Investigation of Thermal Mitigation Strategies for Electroporation-Based Therapies
… of these PEFs results in an increase in the transmembrane potential of all cells within the electric field above a critical value, destabilizing the lipid bilayer of the cellular membrane and increasing the cell-tissue permeability. For years, many have used this phenomenon to assist the …
-
Diverse Effects of Nanosecond Pulsed Electric Fields on Mammalian Cells
… field of sufficiently short duration and higher potential, charges are unable to accumulate sufficiently around the plasma membrane. This allows the applied field to be experienced throughout the interior of the cell. Thus it is proposed that pulsed electric fields of ultra short duration (<1 …
-
Identification and characterisation of proteases in Mycobacterium tuberculosis
… and a Cterminal hydrophobic sequence with a high transmembrane potential. Topology analyses predicted mycosin-1 to be a type I ectoprotein. Consistent with this, expression of mycosin-1 in M. tuberculosis and in Mycobacterium smegmatis transformed with mycP1 (M. smegmatis-P1) was limited strictly …
-
Host cellular defense against metabolic alterations induced by Helicobacter pylori vacuolating cytotoxin A
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
-
The Effects of Neuropathy-Inducing Organophasphate Esters om Chick Dorsal Root Gangli Cell Cultures
… ATP concentrations and changes in mitochondrial transmembrane potential (DYm) following exposure to neuropathy-inducing OP compounds, suggesting that mitochondrial dysfunction occurs. The present dissertation proposed an investigation using chick embryo DRG cultures to explore early mechanisms …
-
Transistor-based biosensing: expanding the functionality of field effect transistors
… as discussed in chapter 3, or to generate a transmembrane potential across a cellular membrane for ultra-localized cell lysis as discussed in chapter 4. These methods expand the functionality of the transistor platform by extending their uses into the realm of sample manipulation. Since the …
Page 1 of 2