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Showing 1 to 1 of 1 for “"transient outward potassium channel"”.
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The role of the perinexus in Long QT Syndrome Type 3
Gain of function of cardiac voltage-gated sodium channel (Nav1.5) leads to Long QT Syndrome Type 3 (LQT3). LQT3 phenotype can be exacerbated by expanding the perinexus, which is an intercellular nanodomain with high density of Nav1.5 in the intercalated disc. Following this finding, we found that …