Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"transgenic mosquito"”.
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Modelling Allee effects in a transgenic mosquito population during range expansion
Mosquitoes are vectors for many diseases that cause significant mortality and morbidity across the globe such as malaria, dengue fever and Zika. As mosquito populations expand their range into new areas, they may undergo mate-finding Allee effects such that their ability to successfully reproduce …
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Identifying Novel Contributors to RNA Interference in Aedes aegypti
… aegypti genome that influence this pathway. A transgenic mosquito strain that reports the status of the siRNA pathway via enhanced green fluorescent protein (EGFP) intensity was employed to differentiate silencing abilities among individuals. Extreme EGFP expression phenotypes, representing …
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Isolation and characterization of dengue virus membrane-associated replication complexes from Aedes aegypti
… (DENV) replication in Aedes aegypti and the mosquito's RNA interference (RNAi) based antiviral response. Here, we have isolated and characterized membrane-bound replication compartments from mosquito cell culture and Ae. aegypti to evaluate the role that these membranes may play in shielding …
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Non-Canonical Odor Coding Ensures Robust Mosquito Attraction to Humans
<p>Aedes aegypti mosquitoes spread deadly diseases, including dengue, Zika, yellow fever, and chikungunya. Only female mosquitoes bite, and they do so because they require a blood-meal for reproduction. Aedes aegypti prefer to bite human hosts, which contributes to their effectiveness as a deadly …
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Gene editing in Aedes aegypti
… is urgently needed. Increased knowledge about mosquito-pathogen relationships and the molecular biology of mosquitoes now makes it possible to generate transgenic mosquito strains that are unable to transmit various parasites or viruses. Ae. aegypti genetic experiments are enabled, and limited …
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Genetically Modifying Mosquitoes Without Compromising Fitness: Can It Be Done?
Malaria is a mosquito-borne disease caused by parasites belonging to the genus Plasmodium. Malaria remains one of the most devastating infectious diseases, killing nearly half a million people each year (WHO 2015). 1,2 With the current increase in drug and insecticide resistance, there is an urgent …
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The early zygotic genes and microRNAs in the yellow fever mosquito Aedes aegypti and the Asian malaria mosquito Anopheles stephensi
Mosquitoes are notorious vectors for multiple diseases like malaria, yellow fever and dengue fever. To manipulate gene expression in mosquito and spread desired genes among natural population for vector control, a thorough understanding of mosquito development and gene regulation is critical. Early …