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Showing 1 to 20 of 117 for “"transforming growth factor-beta"”.

  1. The Participation of Transforming Growth Factor Beta in Tumor Immunoevasion

    … in the presence of high concentrations of TGFbeta1, strong costimulatory strength is permissive for the induction of CD8+ T cells possessing suppressor functions. Our studies also demonstrate that the adoptive transfer of peripherally-induced regulatory CD8+ T cells into recipient mice may …

    uiuc Repository record for The Participation of Transforming Growth Factor Beta in Tumor Immunoevasion (opens in a new tab)

  2. Signal transduction of transforming growth factor-Beta in cytotoxic T cells

    Transforming-Growth-Factor-beta1 (TGF-b1) ist ein multifunktionelles Zytokin, welches insbesondere Zellwachstum und Zelldifferenzierung koordiniert. TGF-b ist vor allem dafür bekannt, Zellen des Immunsystems zu beeinflussen. TGF-b steuert zum Beispiel die Differenzierung von T-Zellen und und deren …

    wurz-thes Repository record for Signal transduction of transforming growth factor-Beta in cytotoxic T cells (opens in a new tab)

  3. Transforming Growth Factor-Beta Signalling in Human Cutaneous Squamous Cell Carcinoma

    … associated with poor survival. <br/><br/>The transforming growth factor-β (TGF-β) signalling pathway is known to play key regulatory roles in skin homeostasis and wound repair. Murine studies indicate that loss of TGF-β signalling is sufficient to drive cSCC, but conclusive evidence for a …

    dundee Repository record for Transforming Growth Factor-Beta Signalling in Human Cutaneous Squamous Cell Carcinoma (opens in a new tab)

  4. The Role of Transforming Growth Factor-Beta In Alcohol-Induced Cardiac Fibrosis

    … </p> <p> cardiac fibrosis, apoptosis, transforming growth factor beta (TGF-β), and the presence of alpha smooth muscle actin (α-SMA)-positive cells were determined. A compensatory period in mice treated with ethanol occurred early followed by a transition to a dilated phenotype over …

    south-carolina Repository record for The Role of Transforming Growth Factor-Beta In Alcohol-Induced Cardiac Fibrosis (opens in a new tab)

  5. Transforming growth factor beta 1 : Role in the progression of chronic renal failure.

    TGF-beta1 plays an important role in the pathogenesis of experimental and clinical glomerulosclerosis and tubufointerstitial fibrosis. Associations have been described between polymorphisms of cytokine and growth factor genes and susceptibility to, or progression of, an increasing number of …

    sheffield-hallam Repository record for Transforming growth factor beta 1 : Role in the progression of chronic renal failure. (opens in a new tab)

  6. The Role of Transforming Growth Factor Beta Signaling in Inflammation-Dependent Colon Cancer

    … (CD) and Ulcerative colitis (UC) are risk factors for colon cancer. TGFβ has been shown to be dysregulated in colon cancer. Bacteria-induced inflammation is necessary for the induction of colon cancer in TGFβ mouse models. However, the mechanism by which TGFβ regulates the inflammatory …

    arizona-thes Repository record for The Role of Transforming Growth Factor Beta Signaling in Inflammation-Dependent Colon Cancer (opens in a new tab)

  7. CROSSTALK BETWEEN LYSOPHOSPATIDIC ACID (LPA) AND TRANSFORMING GROWTH FACTOR BETA (TGFβ) IN BREAST AND OVARIAN CANCER CELLS

    <p>Lysophosphatidic acid (LPA) and transforming growth factor beta (TGFβ) are platelet-derived intercellular mediators of cell proliferation and motility. LPA is a general growth, survival and motility-stimulating factor in mammalian cells. TGFβ prevents proliferation of normal epithelial cells. …

    vcu Repository record for CROSSTALK BETWEEN LYSOPHOSPATIDIC ACID (LPA) AND TRANSFORMING GROWTH FACTOR BETA (TGFβ) IN BREAST AND OVARIAN CANCER CELLS (opens in a new tab)

  8. Chronic kidney disease in HIV populations: prevalence, risk factors and role of transforming growth factor beta (TGF-߀1) polymorphisms

    … to investigate the diagnostic utility of urinary transforming growth factor-beta-1 (TGF-β1) for CKD in the HIV population and determine the association between polymorphisms of TGF-β1 gene and prevalent CKD. Methods: A meta-analysis was performed to document the prevalence of CKD in the global HIV …

    cape-town Repository record for Chronic kidney disease in HIV populations: prevalence, risk factors and role of transforming growth factor beta (TGF-߀1) polymorphisms (opens in a new tab)

  9. Modulating Bone morphogenetic protein (BMP) and Transforming growth factor-beta (TGF-β) signalling with green tea catechins in mammalian cells

    Familial cases of pulmonary arterial hypertension (PAH) are often caused by germline mutations, the most common being a loss of characteristic mutation in the BMPR2 gene, a member of the TGFβ Superfamily. In this study, it was hypothesised that these green tea catechin compounds might inhibit TGFβ …

    bradford Repository record for Modulating Bone morphogenetic protein (BMP) and Transforming growth factor-beta (TGF-β) signalling with green tea catechins in mammalian cells (opens in a new tab)

  10. Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro

    … untersucht die Effekte von Vascular Endothelial Growth Factor (VEGF), Transforming Growth Factor-beta-1(TGF-beta-1), Interleukin-6 (IL-6), Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und Cortisol (bzw. Dexamethason) auf das humane Myokard. Um Rückschlüsse auf mögliche …

    freiburg-diss Repository record for Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro (opens in a new tab)

  11. Targeting the myofibroblast : new strategies in managing equine corneal fibrosis

    … fibrosis, and is initiated by the presence of transforming growth factor beta. Our results indicate that polyethylenimine nanoparticle therapy is safe and effective and when delivering decorin, a natural antagonist of transforming growth factor beta, fibrosis is significantly inhibited in …

    missouri Repository record for Targeting the myofibroblast : new strategies in managing equine corneal fibrosis (opens in a new tab)

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