Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"transdermal patch"”.
-
Development and application of novel approaches to quantitate therapeutic drugs in human blood
… emerging hypothesis that ‘cutting a scopolamine transdermal patch in half will reduce the side effects associated with the medication while still having effective protection from motion sickness’. The validated assay utilised solid-phase extraction coupled to LC-MS to sensitively and accurately …
-
Model-Guided Transdermal Formulation of 1α,25-Dihydroxyvitamin D3 for Improved Safety and Efficacy
… to cause hypercalcemia. Our aim is to develop a transdermal formulation of 1,25(OH)2D3 that allows for controlled drug delivery with minimal stimulation of the intestinal calcium ion channel (TRPV6), thereby avoiding the toxic outcome of hypercalcemia. By incorporation an ethylene vinyl acetate …
-
A Quantitative Study of Drug Recrystallization in Drug-In-Adhesive Transdermal Patches Using Vibrational Spectroscopy
<p>Drug-in-adhesive (DIA) transdermal patches are an important type of transdermal drug delivery system (TDDS). The drugs used in the DIA system are frequently present in metastable forms, such as amorphous solids or supercooled liquids. These drug states are thermodynamically unstable and tend to …