Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1350 for “"transcription factors"”.
-
Intrinsic Disorder in Transcription Factors
… need for disorder-associated signaling and transcriptional regulation in nucleated cells. The major advantage of intrinsically disordered proteins or disordered regions is their inherent plasticity for molecular recognition, and this advantage promotes disordered proteins or disordered …
-
Coregulatory Transcription Factors and Spermatogenesis
The BTB was hypothesized to be deficient in Etv5 -/- mice, and that this was mediated by Claudin 5 (CLD5). In both Etv5-/- and W/Wnu mice, the BTB was leaky. Examination of CLD5 expression among mice of various ages and phenotypes revealed the following: both ETV5 and germ cells were necessary for …
-
Combinatorial gene regulation by transcription factors
… and promoters in the form of binding sites for transcription factors (TFs), which collaboratively recruit the transcriptional machinery and drive gene expression. Using high-throughput and quantitative technologies developed by our lab and others, we studied TF binding sites in enhancers from …
-
Evolution of Sp Transcription Factors in Metazoans
Die Mechanismen der Kopfentwicklung bei Arthropoden sind weit weniger gut verstanden als die Mechanismen der Entwicklung des Thorax und des Abdomens, wie Daten aus der Fruchtfliege Drosophila melanogaster gezeigt haben. Die posterioren, gnathocephalen Kopfsegmente (Mandibular-, Maxillar-, …
-
PLANT TOLERANCE TO DROUGHT: MODULATION OF TRANSCRIPTION FACTORS
Water scarcity is a serious problem that will be exacerbated by global climate change. Massive quantities of water are used in agriculture, and abiotic stresses, especially drought and increased salinity, are primary causes of crop loss worldwide. Various approaches may be adopted to consume less …
-
Analysis of transcription factors under sulphur deficiency stress
… involved in sulphate metabolism are regulated on transcriptional level by products of other genes called transcription factors (TF). Several published experiments revealed TF genes that respond to sulphate deprivation, but none of these have been so far been characterized functionally. Thus, we …
-
Subcellular Localization of Nicotiana tabacum TGA Transcription Factors
Die Salicylsäure (SA) ist ein wichtiges Signalmolekül bei der Regulation der pflanzlichen Pathogenabwehr. as-1-ähnliche cis-Elemente in den Promotoren von vielen Abwehrgenen vermitteln SA- und auch Auxin-induzierbare Genexpression. Diese Elemente werden vom ASF-1/SARP-Proteinkomplex erkannt, dessen …
-
Archaeal Basal Transcription Factors: DNA and Protein Interactions
The archaeal basal transcription system is a stripped-down model of the complex eucaryal one, having only one RNA polymerase and two known and characterized basal factors: Transcription Factor B (TFB) and TATA-Binding Protein (TBP). After the first sequence analysis of an archaeal genome (Bult et …
-
V-ATPase regulation of Hypoxia Inducible transcription Factors
… under low oxygen tensions by initiating a transcriptional cascade centered on the action of Hypoxia Inducible transcription Factors (HIFs). In aerobic conditions, HIFs are inactivated by ubiquitin-proteasome-mediated degradation of their a subunit, which is dependent on prolyl hydroxylation …
-
Compensation Between Foxp Transcription Factors Maintains Proper Striatal Function
… behavior. Mutations in the regulatory transcription factors expressed in SPNs can result in neurodevelopmental disorders (NDDs). Paralogous transcription factors Foxp1 and Foxp2, which are both expressed in the dopamine receptor 1 (D1) expressing SPNs, are known to have variants …
-
CREB transcription factors and long-term memory in Drosophila
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1995.
-
General Transcription Factors Play Dual Roles In Initiation And Termination
… and the terminator regions of a gene during transcription, is emerging as an important gene regulatory mechanism in eukaryotes. The role of promoter bound general transcription factors during initiation is well established. However, recent studies have revealed that some initiation factors …
-
Roles of Myocardin-Related Transcription Factors in Muscle and Brain
Partnerships between DNA binding transcription factors and transcriptional cofactors govern gene transcription in various developmental and tissue contexts, particularly during cardiovascular and neuronal development. This dissertation aims at studying the in vivo relevance of the partnership …
-
Evolutionary and functional analysis of transcription factors controlling leaf development
… on a proper control of gene expression. Transcription factors (TFs) are global regulators of gene expression that play essential roles in almost all biological processes among eukaryotes. This PhD project focused on the characterization of the sink-to-source transition of Arabidopsis …
-
Modelling transcription factors diffusion in 3D using Hi-C data
The influence of the transcription factors (TFs) as a result of their interaction with the genetic material made it subject to a lot of studies. From roles of TFs in shaping the DNA landscape, to their functionality and purpose in cell cycle and identity, these DNA binding molecules can upregulate …
-
Biophysical analysis of MarR family transcription factors from Streptomyces coelicolor
… proteins (MFRs) represents an important group of transcriptional regulators. Named after the first to be characterized in Escherichia coli, the multiple antibiotic resistance repressor (MarR), the members of this family are involved in a number of biological processes which include antibiotic …
Page 1 of 68