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Showing 1 to 2 of 2 for “"transcription coregulators"”.

  1. Regulation of Pyruvate Dehydrogenase Kinase 4 by Thyroid Hormone / Role of Peroxisome Proliferator Activated Receptor Gamma Coactivator-1 alpha and Ccaat Enhancer Binding Protein

    … the role of the thyroid hormone receptor (TR), transcriptional coactivators especially the peroxisome proliferator activated receptor gamma coactivator-1 (PGC-1α) and other transcription factors that act as accessory factors in T3 actions. </p> <p>Thyroid hormone receptors (TRα or TRβ) are part …

    tenn-hsc Repository record for Regulation of Pyruvate Dehydrogenase Kinase 4 by Thyroid Hormone / Role of Peroxisome Proliferator Activated Receptor Gamma Coactivator-1 alpha and Ccaat Enhancer Binding Protein (opens in a new tab)

  2. Mechanistic Studies Of A Novel Ppar-Gamma Mutant That Causes Lipodystrophy And Diabetes

    … moderately or severely defective at inducing transcription from most promoters, without dominant negative activity. This suppression of transcriptional activity may be mediated by an increased effect of nuclear receptor corepressors on E157D PPAR-gamma. In addition, the mutant binds atypical …

    wayne-thes Repository record for Mechanistic Studies Of A Novel Ppar-Gamma Mutant That Causes Lipodystrophy And Diabetes (opens in a new tab)