Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"transcellular transport"”.
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Analysis of a model to describe lead transport by the small intestine
Investigations into the mechanism of lead transport across the rat small intestine were conducted using the in vitro everted sac technique. The data obtained were used to construct a model which could competently rationalise some of the reported observations in the literature concerning intestinal …
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A Transmembrane Precursor of Secretory Component
… and is thought to be the receptor mediating the transcellular transport of pIg. We studied the biosynthesis and processing of rabbit and human SC. Using translation of mRNA from rabbit mammary gland and liver in a cell-free system supplemented with dog pancreas microsomal vesicles, we discovered …
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IN VITRO LUNG EPITHELIAL CELL TRANSPORT AND ANTI-INFLAMMATORY ACTIVITY FOR LIPOSOMAL CIPROFLOXACIN
… enables slower and sustained lung epithelial transport and uptake, compared to CPFX, thereby producing prolonged local pharmacological actions. The human bronchial epithelial Calu-3 cells were used as monolayers to characterize the kinetics and mechanism of transport and/or uptake, and to …
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Regulation of sodium channel densities in A6 renal epithelial cells by hormonally-dependent mechanisms
… (ENaC) located in the apical membranes of transporting epithelia, such as cells of the renal distal nephron, constitute the rate limiting step in the transcellular transport of sodium. The regulation of sodium ion reabsorption in the kidney, which is essential for salt and water …
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Transport of Antibodies and Nanoparticles across An in vitro Blood-Brain Barrier
… and NPs, it is necessary to quantify their transport parameters across the BBB and understand the underlying transport mechanisms. In this study, we used an in vitro BBB model of a cultured cell monolayer from an immortalized mouse cerebral microvascular endothelial cell line, bEnd3. …
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Improving CNS Delivery of Genistein for the Treatment of Sanfilippo Syndrome
… metabolism, enterohepatic recycling and efflux transporters are few factors that are thought to be responsible for poor penetration of genistein into the brain. We aim to develop strategies to increase genistein concentration in the CNS, decrease the level of heparan sulfate in the CNS and thus …