Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"transamidation"”.
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Mechanisms of Non-Enzymatic Peptide Bond Formation: Thioester and Transamidation Routes
… under mild prebiotic conditions presented the transamidation and thioester routes as possible methods for ancestral peptide (amide) bond formation.</p>
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Regulation of Transglutaminase by 5-HT2A Receptor Signaling and Calmodulin
… and calmodulin (CaM) regulate TGase-catalyzed transamidation of Rac1 and htt in cultured neuronal cells and HD transgenic animals, respectively.</p><p>5-HT2A receptors are G-protein coupled receptors which are widely expressed in the brain, peripheral vasculature, platelets and skeletal muscle. …
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Structural And Functional Characterization Of Proteins Of Unknown Function (hp0495, Hp0100 And Hp1259) In Helicobacter Pylori
… ND-AspRS, AdT, and Hp0100 and facilitates AdT's transamidation process of Asp-tRNAAsn (~ 35-fold) and Glu-tRNAGln (~ 3-fold). Our work characterizing the Asn-transamidosome and transamidation of Asp-tRNAAsn was published in 2013 (Silva, G. N., Fatma, S., et al. J. Biol. Chem. 288, 3816). An …
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Expression and function of transglutaminase 1 in the brain
… cross-linking enzymes catalysing a transamidation reaction between a protein-bound glutamine residue and a small primary amine or a protein-bound lysine residue. Transglutaminase 1, a member of this family, is expressed in different epithelial and endothelial tissues. Recently …
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Biochemical And Structural Characterization Of The Core Subunits Of Gpi Transamidase
… was used to study the enzyme's behavior on transamidation in vivo. </p> <p> Due to the complex nature of this protein and the fact that it is membrane associated, we set out to simply this enzyme into a more tractable system. In chapters 2 and 3 of this thesis, we focused on the soluble …
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Assembly And Function Of Macromolecular Complexes For Accurate Trna Aminoacylation In Helicobacter Pylori
… corresponding acceleration in the rate of AdT transamidation of either Asp–tRNA<sup>Asn</sup> or Glu–tRNA<sup>Gln</sup>. Overall, our results highlight the importance of the novel ATPase Hp0100, for the indirect biosynthesis of Asn–tRNA<sup>Asn</sup> and Gln–tRNAGln in <i>H. pylori</i>. </p> …
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Influence of climate changes on cross allergies: possible involvement of pollen transglutaminase
… This enzyme can be involved also in the transamidation of proteins present in the human mucosa interacting with surface pollen or, finally, the enzyme itself can represent an allergen, as suggested by studies on celiac desease. I have hypothesized that this pollen enzyme can be affected …