Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 100 for “"tpp"”.
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Design and Synthesis of Thiamine Pyrophosphate (TPP) Analogues for Investigating the Structure-Activity Relationship (SAR) of Inhibitors of TPP-dependent Enzymes
Thiamine pyrophosphate (TPP), the bioactive form of vitamin B1, is an essential coenzyme needed for processes of cellular metabolism in all organisms. TPP-dependent enzymes all require the coenzyme TPP for catalytic activity, although individual members vary significantly in substrate preferences …
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Structures of oxalate oxidoreductase : C₂ activation by a microbial TPP-dependent ferredoxin oxidoreductase
… electrons. OOR uses a thiamine pyrophosphate (TPP) cofactor to cleave the C-C bond, and three [4Fe-4S] clusters to capture and transfer the electrons produced. Both of these products from oxalate degradation, CO 2 and the low-potential electrons, allow M thermoacetica to grow via the …
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Interactions with bioenergetics by the mitochondria-targeted anti-apoptotic imidazole fatty acid derivative ‘TPP-IOA’.
… brain, heart). Recently, the small molecule ‘TPP-IOA’ was designed to target mitochondria and therein inhibit the peroxidase activity of cytochrome c that promotes activation of the apoptotic death pathway (Atkinson et al., Nat. Commun. 2011; 2:497). Therefore, TPP-IOA holds promise as a …
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Study of the Valence Tautomer Complex [Co(sq)(cat)(3-tpp)2] for Applications in Molecular Spintronics
… of the valence tautomer molecule [Co(sq)(cat)(3-tpp)2] is presented. In the first chapter, the phenomenon of valence tautomerism (VT) occurring in coordination compounds is introduced and described from the perspective of Crystal Field Theory (CFT). Further, the molecular structure and physical …
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Porphyrins and metalloporphyrins as field-responsive materials
… porphyrinate polymer: \lbrack Fe$\sp{\rm II}$(TPP)(pyCN)\rbrack$\sb\infty$ (where TPP = 5,10,15,20-tetraphenylporphyrinate(2$-$); pyCn = 4-cyanopyridine); iron(III) porphyrinate polymers: \lbrack Fe$\sp{\rm III}$(TPP)(4-MeIm)\rbrack$\sb\infty$, \lbrack Fe$\sp{\rm …
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Use of natural enemies to achieve biological control of the severe and persistent glasshouse pest, the potato-tomato psyllid : A thesis submitted in partial fulfilment of the requirements for the Degree of Doctor of Philosophy at Lincoln University
The tomato-potato psyllid (TPP), Bactericera cockerelli, is a serious pest of solanaceous crops. Several populations of TPP have become pesticide-resistant, increasing the need for alternative control options, such as biological control. However, biological control of TPP has remained challenging. …
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Tuning the ground and excited state properties of a series of polymetallic tridentate complexes incorporating Ru(II) or Os(II) as the chromophore
… the tridentate polypyridyl bridging ligand tpp (where tpp = 2,3,5,6-tetrakis(2-pyridyl)pyrazine) and an investigation of their ground and excited state properties. A series of ruthenium monometallic chromophore complexes has been prepared varying the ligands coordinated on the metal center. …
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Stability and Morphological Evolution in Polymer/Nanoparticle Bilayers and Blends Confined to Thin Film Geometries
… silsesquioxane (POSS), trisilanolphenyl-POSS (TPP) is explored at elevated temperatures. The results demonstrate unique dewetting morphologies in both PtBA/TPP and PS/TPP bilayers that are significantly different from those typically observed in dewetting polymer/polymer bilayers. Upon …
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Identification and analysis of Arabidopsis thiamine pyrophosphate transporters
Thiamine pyrophosphate (TPP) serves as a cofactor in universal metabolic pathways, including glycolysis, the pentose phosphate pathway (PPP) and the tricarboxylic acid cycle; moreover, it is essential for the proper functioning of all organisms. Recently, several steps of the plant thiamine …
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Quartz Crystal Microbalance Studies of Dimethyl Methylphosphonate Sorption Into Trisilanolphenyl-Poss Films
… a CWA simulant, into trisilanolphenyl-POSS (TPP) films has previously been characterized with reflection absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and uptake coefficient determinations [1]. In our study, the quartz crystal microbalance (QCM) is used to study the …
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The Synthesis and Photophysical Properties of New Polymetallic Complexes Designed for Use in Photoinitiated Electron Collection
… bridging ligands 2,3,5,6-tetra(pyridyl)pyrazine (tpp) and 2,2'-bipyrimidine (bpm). The symmetric bidentate ligand 4N-perylene was designed and the majority of the synthesis was completed. The bimetallic complexes [(tpy)M(tpp)Ru(LLL)]²⁺, where M = Ru or Os and LLL = Cl₃, (CH₃CN)₃, tpp, or (dpq)Cl, …
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Supramolecular organisation, conformation and electronic properties of porphyrin molecules on metal substrates
… by coordinating tetraphenyl porphyrin (TPP) macrocycles with cerium. The influence of the metal center on the porphyrins’ electronic structure was investigated via STS for TPP, TPyP,Fe−TPyP, Fe−TPP, Ce−TPP, and Co−TPP, whereby the inhomogenous electron density distribution associated …
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Molekulare Dynamik in binären Glasbildnern studiert mittels 31P- und 2H-NMR
… am System Tripropylphosphat (TPP, Tg = 135K) / Poly(styrol) (PS, Tg = 335K) vorgestellt. Messungen wurden mittels 31P- und 2H-NMR sowie Differenzkalorimetrie (DSC) ausgeführt, Ergebnisse der dielektrischen Spektroskopie (DS) sowie der depolarisierten dynamischen Lichtstreuung …
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New composite coagulant from agro-waste (tapioca peel) and polyaluminium chloride for primary landfill leachate treatment
… of natural material (tapioca peel powder (TPP)) originated and recycled from agro-waste in this study. The limited ability of TPP as a single coagulant could be overcome by substituting the material into polyaluminium chloride (PAC) as a composite coagulant (PACTPP) with different weight …
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Creative Arts Therapies and Empirically Supported Treatments for Trauma: Differences in Treatment Preferences by Personality Type and Trauma Severity
… predicting Trauma Perception and Preference (TPP) scores for Music therapy, Art therapy, and PE, agreeableness predicting TPP scores for PE, extraversion predicting TPP scores for CPT, and neuroticism scores predicting TPP scores for PE. Trauma exposure was not found to significantly predict …
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Chemical Strategies for Delivery of Compounds to Mitochondria
… moiety to a triphenylphosphonium cation (TPP), which drives membrane potential-dependent uptake into the organelle. However, there are still limitations associated with TPP-targeting, some of which I have attempted to overcome in this work. Firstly, I have investigated the use of labile …
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Étude structurale des riborégulateurs thiB et thiM
… riborégulateurs lient la thiamine pyrophosphate (TPP) : le riborégulateur thiB qui contrôle le transport de TPP, le riborégulateur thiM qui encode le gène du sauvetage de TPP et le dernier, le riborégulateur thiC qui est parmi les gènes régulant la synthèse de TPP. Mes travaux de recherche portent …
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Structural insights into conformationally-gated reactions catalyzed by thiamine pyrophosphate-dependent enzymes
Thiamine pyrophosphate (TPP)-dependent enzymes utilize TPP as a biological carbanion to initiate reactions on substrates with carbonyl carbon(s), such as pyruvate and 2-oxoglutarate, two central metabolites. This thesis presents structural analyses of three TPP-dependent enzymes. Most …
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Encapsulation of iron(III) protoporphyrin IX and tetraphenylporphyrin in metal-organic frameworks for application as heterogeneous oxidation catalysts
… and Fe(III) tetraphenylporphyrin (Fe(III)TPP). Methyl orange (MO) adsorption was used as an initial model for substrate uptake in MOFs 1 and 2. MOF 1 showed good adsorption of MO (10.3 ± 0.8 mg.g-1 ) which could undergo in situ protonation upon exposure to aqueous HCl vapour. By contrast …
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