Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"toxicological analysis"”.
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Toxicological Analysis of Acaricides for Varroa Mite Management
… resistance in mite populations. I report a toxicological analysis of stilbene products against acaricide-susceptible and -resistant mites. My results find a significant increase in metabolic detoxification enzyme activities in acaricide-resistant mites compared to susceptible mites. …
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Toxicological Analysis of Tacrines and Verapamil on the Yellow Fever Mosquito, Aedes aegypti
Mosquitoes affect human health worldwide as a result of their ability to vector multiple diseases. Mosquitocide resistance is a serious public health challenge that warrants the development of improved chemical control strategies for mosquitoes. Previous studies demonstrate the mosquito blood-brain …
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Toxicological Analysis of the Neonicotinoid Insecticide Imidacloprid to Honey Bees, Apis mellifera, of Different Colonies
… mortality to the honey bees. A comparative analysis of GST kinetic activity from imidacloprid-susceptible and -insensitive honey bees revealed a lower bimolecular inhibition rate constant (ki) for imidacloprid-insensitive individuals (5.07 ± 0.098 nmol/min/mg protein) compared to the …
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Post-mortem toxicological analysis of hair in violent fatalities: an investigation into long-term drug exposure
… River Mortuary (South Africa). A qualitative toxicological analysis was performed in 90 hair samples using a SCIEX X500R QTOF. Variables pertaining to the colour and length of the hairs were recorded. The majority of the hair samples were black (n=79), while others were black and white (n=5), …
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A Toxicological Analysis of Exposure Magnitude, Duration, and Frequency and the Significance for Monitoring and Management of Episodic Pollution Events
… and appropriate models were used to expand the analysis of organism effects to additional exposure scenarios. Ceriodaphnia dubia and fish population models were used to evaluate population level and even community level responses to intermittent disturbances. Effects at the population level …
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A toxicological analysis of the cyanotoxin β-methylamino-L-alanine at multiple neural levels and identification of novel modes of activity
… and cell cycle and apoptosis. Cell cycle analysis of OECs treated with BMAA resulted in cell cycle arrest at the G2/M phase.
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Assessment of the suitability of blood samples collected for toxicological analysis for subsequent genetic analysis: A follow-up study one year later
… sample from the deceased individual for genetic analysis. It was therefore important to determine the suitability of blood samples collected and handled in toxicology environments for subsequent genetic tests. Previously, blood samples from 30 post-mortem cases were collected into two red-top (no …
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Investigating the role of routine drug analyses in survivors of sexual offences admitted to the clinical forensic unit at Victoria Hospital
Introduction: Toxicological analysis is an important component of drug-facilitated sexual assault (DFSA) investigations, as it allows for identification and interpretation of substances involved. Currently, forensic toxicological analyses are not routinely provided to DFSA survivors in South …
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The development of appropriate methods for drug analysis at the Forensic Chemistry Laboratory, Cape Town
… an improved extraction procedure for systematic toxicological analysis. The scope of the study was therefore twofold. Firstly, a study was undertaken of unnatural deaths in the greater Cape Town area for which samples would not normally have been submitted.
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Interferência de medicamentos em exames laboratoriais.
… of drugs in tests performed in clinical and toxicological analysis is of paramount importance in routine laboratory t ests to interfere in and modify the clinical laboratory diagnosis, which leads to a negative false or positive f alse result, pseudo - increase or pseudo - decrease . The …
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Origins And Development Of Forensic Medicine And Forensic Science In England, 1823-1946
… sciences of special pathology and Home Office toxicological analysis by the 1900s and it is shown that in creating forensic science in the 1930s on this elite medical model as an aid to police investigations, other science and medicine in court, particularly in the civil courts, were excluded …
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Post-mortem toxicological investigations in a paediatric population
… for post-mortem medico-legal examinations,as toxicological investigations are not routinely performed. It was hypothesised that drugs would be detected in sudden and unexpected death ofinfant (SUDI) cases admitted to Salt River Mortuary (SRM), as infantsform a vulnerable population. Biological …
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Investigating post-mortem redistribution of drugs in a cohort of suspected unnatural deaths in Cape Town South Africa
Introduction: The interpretation of post-mortem toxicological analysis results is complex, specifically, due to the phenomenon of post-mortem redistribution (PMR). The later needs to be taken into consideration when determining if, and to what extent a drug contributed to death. Additionally, case …
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Investigating the role of commonly misused drugs in suspected unnatural and/or unexplained deaths in Cape Town in 2022
… suicides, and accidental deaths, often require toxicological analysis to assist with determining the cause of death. In 2022, the Forensic Toxicology Unit within the Western Cape Forensic Pathology Service piloted a targeted drugs analysis at Salt River Mortuary in Cape Town. This permitted an …
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A post-mortem toxicological investigation: Understanding the role of drugs of abuse in violent fatalities in Cape Town, South Africa
… within the Western Cape Province. The use of toxicological findings from victims of violent death (homicides, suicides, and accidents) to examine community-specific drug-related violence is slowly increasing in different parts of the world. In South Africa, however, monitoring drug trends in …
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Development of a GC-MS method to determine toxic alcohols and their metabolites in postmortem blood
… these are not routinely investigated in forensic toxicological analysis of biological samples. The purpose of this study was to modify and characterise a gas chromatography-mass spectroscopy (GC-MS) method for the quantitative determination of ETG, DEG, 1,4-BD, PGL, and the toxic metabolite of …
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Toxicological Findings in Fatal Road Traffic Accidents in Cape Town: A Pilot Study
… rates are higher than the average global burden. Toxicological analyses in cases of RTA fatalities are not performed routinely in SA (apart from alcohol analysis), thus understanding the burden of other drug impairment on road traffic deaths is limited. Aim: A prospective toxicological analysis …
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A comparison of derivatisation procedures for the detection of multiple analytes in systematic forensic toxicology
… for their general applicability to systematic toxicological analysis (STA) involving (a) acylation with pentafluoropropionyl anhydride (PFPA) and pentafluoropropanol (PFP-OH), (b) acylation/esterification (methylation) with pentafluoropropionyl anhydride (PFPA) and a novel methylating agent …
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NEUROBIOLOGIA DEL SUICIDIO NEL DISTURBO DEPRESSIVO MAGGIORE: STUDIO MORFOLOGICO POST-MORTEM PER L¿INDAGINE DEL NETWORK GLIALE E VASCOLARE, CON ANALISI TOSSICOLOGICHE PER LA VALUTAZIONE DELL¿ADERENZA ALLA TERAPIA PSICHIATRICA
… underlying this thesis focused on the postmortem analysis of human brain tissue from individuals diagnosed with MDD who died by suicide, with the aim of investigating alterations in the glial network—astrocytes and microglia—as well as in cerebral vascularization, in brain regions involved in mood …
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RILIEVO DI FATTORI XENOBIOTICI, CON PARTICOLARE RIFERIMENTO A NICOTINA E COTININA, IN CAMPIONI ISTOLOGICI APPARTENENTI A FETI E NEONATI DECEDUTI PER CAUSE NATURALI.
… have been analyzed first by screening tests for toxicological substances and then by ICP-MS analysis for 61 different metals. At last, all the 151 samples have been subjected to UPLC/MS-MS technique for the relief and dosage of nicotine and cotinine.