Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 3027 for “"toxicity"”.
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Molecular toxicity of lead
Thesis: S.B., Massachusetts Institute of Technology, Department of Earth, Atmospheric, and Planetary Sciences, 2008.
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Statin-induced muscle mitochondrial toxicity
… dose range for subsequent mitochondrial toxicity experiments. Lastly, mtDNA content and expression was quantified in skeletal muscle biopsies collected from 10 patients with statin-induced rhabdomyolysis (SIR) and compared to 8 healthy controls to investigate whether muscle mtDNA is …
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Glutamate and MDMA Neurobehavioral Toxicity
… the glutamatergic neurotransmitter system. Excitotoxicity resulting from excessive glutamate release has the potential to contribute to the long-term toxicity of MDMA, including neurochemical and behavioral deficits. The purpose of the present study was to assess the effect of repeated MDMA …
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Superoxide Toxicity in Escherichia Coli
Very little is understood about the physiology of the periplasm. of gram negative bacteria. The presence of CuZnSOD within that compartment in several different species suggests that oxidative damage occurs there. We studied the regulation of sodC, the gene that encodes CuZnSOD, and the phenotypes …
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Lead Toxicity in Experimental Animals
Made available in DSpace on 2015-05-12T22:36:27Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7309963.PDF: 3412457 bytes, checksum: ccc6fb957474d13b6f20897e92f9b2d0 (MD5) Previous issue date: 1972
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Mechanisms of microcystin-LR toxicity
Microcystin-LR (MCLR) is a cyanobacterial hepatotoxin that inhibits serine/threonine protein phosphatases types 1 and 2A in hepatocytes in vivo and in vitro, and disrupts actin microfilament (MF), microtubule (MT) and intermediate filament (IF) networks. The sequential ultrastructural and …
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Studium toxicity PFAS s využitím řas
… all PFAS are still on the market. In this paper, toxicity was assessed for three substances that are banned PFOS (Perfluorooctanesulfonic acid), PFOA (Perfluorooctanoic acid) and PFHxS (Perfluorohexanesulfonic acid) and for two substances that are still on the market GenX (HFPO-DA, …
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Methotrexate associated toxicity in rheumatoid arthritis
Contains fulltext : 146888.pdf (Publisher’s version ) (Open Access)
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Effect of diet on methotrexate toxicity
… different diets and regimens on gastrointestinal toxicity induced by methotrexate (MTX) in rats. Toxicity was determined by severity of anorexia and incidence of diarrhea on d 3 and 4 following an intraperitoneal injection of 20 mg MTX per kg body weight. Rats adapted to a casein-based …
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Leveraging cell micropatterning technology for rapid cell-based assessment of chemical toxicity and population variation in toxicity susceptibility
… presents a unique and costly challenge to toxicity testing in the 21 st century. In recent years, the United States has seen large coordinated efforts across governmental agencies to shift from expensive and slow traditional in vivo tests to more affordable and higher throughput in vitro …
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Amiodarone-induced pulmonary toxicity in F344 rats
… drug despite its potentially fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to develop and characterize a rat model of amiodarone-induced pulmonary toxicity (AIPT). A protocol was developed in which male F344 rats were instilled intratracheally …
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Developmental Toxicity of Organophosphate-Based Flame Retardants
… concerns about persistence, bioaccumulation, and toxicity, PentaBDE was voluntarily phased out, prompting an industry-wide shift toward the use of alternative flame retardant formulations containing at least one of the two major classes of organophosphate-based flame retardants (OPFRs) - …
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NEONICOTINOID TOXICITY IN REPRODUCTIVE HONEY BEE CASTES
… on developing queens. We found that direct THI toxicity in queens can result in hypoplasia of the pheromone producing mandibular glands. Such morphologic organ changes precede compromised organ function. Therefore, it is reasonable to hypothesize that dysregulation and disruption of pheromone …
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Radiotherapy induced toxicity in lung cancer patients
Contains fulltext : 194287.pdf (Publisher’s version ) (Open Access)
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Modelling bioaccumulation and toxicity of metal mixtures
Contains fulltext : 100831.pdf (Publisher’s version ) (Open Access)
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Aquatic toxicity of one dimensional carbon nanomaterials
This study determined the toxicity of one dimensional carbon nanomaterials (CNMs) to amphipods, midge, oligochaetes and juvenile mussels in water and sediment. As-produced or modified carbon nanotubes (CNTs) and silicon carbide nanowires (SiCNW) were selected to represent CNMs. Sediment tests were …
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