Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"topical microbicide"”.
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IN VITRO SUSCEPTIBILITY OF CHLAMYDIA TRACHOMATIS TO LPS-BINDING POLYAMINES AND CELLULOSE ETHER POLYMERS: TOWARDS THE DEVELOPMENT OF A MICROBICIDE AGAINST CHLAMYDIA INFECTION
… focused on development of a vaginally-delivered topical microbicide as an alternative strategy for prevention of Chlamydia. The paucity of a well-established method suitable for large-scale analysis of in vitro Chlamydia infection is a major limitation in the development of novel anti-Chlamydia …
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Dendronized Amphiphilic Copolymers Synthesized from Methacrylate Derivatives as Potential Topical Microbicides
… HIV, other STDs and mucosal pathogens is urgent. Topical microbicides based on amphiphilic compounds have been identified as an attractive means toward this goal. Novel dendritic methacrylate macromonomers––di-tert-butyl …
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Development of Closomer And MIBG based Nanoformulation: Application to HIV Prevention and Neuroblastoma Therapy
… can be a promising platform used for delivery of topical antiviral or other bioactive agents. In Chapter 6, it was hypothesized that meta-iodobenzylguanidine (MIBG) complexation with VP-16 will improve drug solubility and specificity towards BE(2)C neuroblastoma (NB) cells, 90% of which are known …
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Development and Evaluation Of HIV gp120 Responsive Microbicide Formulation for the Prevention of HIV Sexual Transmission
… Thus, there is an urgent need to develop topical (vaginal/rectal) microbicide formulations capable of preventing HIV sexual transmission. The objective of this dissertation is to develop a mannose specific, lectin-based topical microbicide formulation capable of targeting HIV gp120 for the …