Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"toll-like receptor4"”.
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Role of TRB3 in Glucose Enhancing Effect on LPS-induced NO Production
TRB3 (Tribbles homolog 3)는 pseudokinase로 알려져 있으며, 세포 내 에너지 대사에 관여할 뿐만 아니라 염증반응 그리고 세포 사멸을 통한 pathological 과정에 관여한다. TRB3의 발현은 영양 상태에 따라 조절된다. 주로 저포도당 (fasting) 상태에서 증가하는 TRB3는 pro-inflammatory cytokine 을 조절하는 NF-κB의 활성화를 저해하는 것으로 알려져 있다. 선행연구에서 포도당농도 변화 따른 LPS에 의해 유도되는 NO생성 변화를 관찰한 결과, TRB3 및 …
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Acute pancreatitis, from local defense to remote organ injury
… in the pancreas. This response was mediated via Toll like receptor-4 and involved both MyD88-dependent and –independent pathways. We propose that HS has a role in the monitoring of pancreatic tissue well-being. Acute lung injury is the most common extra-pancreatic complication in the acute …