Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"tissue staining"”.
-
Role of BDNF-TrkB Signaling in Cocaine Addiction
… did not confirm these results. Preliminary tissue staining demonstrated similar levels of viral infectivity between AAV-GFP and AAV-TrkB WT; however, subsequent tissue staining demonstrated very weak to no viral expression, consistent with the lack of consistent behavioral results. Finally, …
-
FANCD2 in relation to BRCA2 mutated breast cancer
… and FANCD2, take over (Kais et al., 2016). Tissue staining for the active unit of telomerase (hTERT) and FANCD2 was performed on 470 BC samples on tissue microarrays (TMAs). It was evaluated whether overexpression of these proteins in the cell nuclei were associated with clinicopathological …
-
Identification of differentially expressed genes in breast cancer tissues and cells
… changes in normal versus malignant breast tissue. It was also used in a defined cell culture system having differential cellular characteristics, to identify genes that may be responsible for different biological behavior of these cell lines. Messenger RNA from normal, breast cancer …
-
Human adaptation of avian influenza viruses
… including dose dependent glycan binding, human tissue staining and structural modeling. Using these complementary analyses, it is shown that molecular interactions between amino acids in and proximal to the RBS, including interactions between the RBS and the glycan receptor converge to provide …
-
Glycan receptor binding determinants of Influenza A virus hemagglutinin
… including dose-dependent glycan binding, human tissue staining and structural modeling. Using these complementary analyses, it is shown in this thesis that the molecular interactions between amino acids in and proximal to the RBS (referred to as amino acid interaction networks), including those …
-
The Neurotrophic Influence on Craniofacial Development Subsequent to in Utero Unilateral Transection of the Trigeminal(V) Nerve
… in the regulation of cellular differentiation, tissue morphogenesis, subsequent development and growth, and maintenance of the craniofacial complex. This research is believed to be the first time that such a procedure has been attempted on a mammalian fetus. Each animal was clinically evaluated …
-
Development of polymer-coated nanoparticle imaging agents for diagnostic applications
… imaging agents for use in blood, cell and tissue diagnostic applications. Low-molecular weight, amphiphilic polymers capable of noncovalent interactions with nanoparticle surface ligands and the aqueous environment were synthesized and characterized for use in nanoparticle coating …
-
Submicron-resolution Photoacoustic Microscopy of Endogenous Light-absorbing Biomolecules
… optical wavelength, at <1 mm depth in biological tissue (the optical ballistic regime). OR-PAM has been applied successfully to structural and functional imaging of blood vasculature and red blood cells in vivo. Any molecules which absorb sufficient light at certain wavelengths can potentially be …
-
Integrin alpha6beta4 contributions in pancreatic adenocarcinoma
… of chronic pancreatitis samples resembled the staining pattern of normal pancreas. When cancer was present in areas of chronic pancreatitis, this altered expression of alpha6beta4 integrin identified the cancer. These results indicate that the early overexpression of the alpha6beta4 integrin in …
-
Interrogating structure-function relationships in the pathogenesis and treatment of human disease : insights into the development of therapeutics for emergent tropical viruses
… was compared to other experiments, including tissue staining and in vitro replication, to determine that this seal H3N8 virus is unlikely to infect and spread within human populations. These insights further our understanding of how complex ensembles of glycans can influence susceptibility to …
-
Innate and humoral immune responses to HIV-1
… binding studies and immunohistochemistry. Tissue staining with 4E10 demonstrated reactivity consistent with the type 1 inositol trisphosphate receptor as the most likely candidate autoantigen. These results demonstrate that 4E10 recognition of liposomes competes with MPER recognition and …