Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"tissue properties"”.
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A Patient-specific Irreversible Electroporation Treatment Planning Model Based on Human Tissue Properties
… relies on the electrical response of human tissue during IRE. This work quantifies this response for the first time and implements human tissue properties in a patient-specific, 3D treatment planning model.
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Neural and Collagen Tissue Properties As They Relate to Glenohumeral Joint Laxity and Stiffness
… associated with capsule and labrum injury, the tissue characteristics of the capsule and labrum are not well understood. Therefore, we sought to explore the tissue properties of the capsule and labrum. We also explored the relationship between the tissue properties and passive joint motion. To …
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Injury Mechanisms, Tissue Properties, and Response of the Post-Mortem Human Abdomen in Frontal Impact
… was to characterize abdominal injury mechanisms, tissue failure thresholds, and internal organ response to blunt impacts of the abdomen. Field accident data from the Crash Injury Research and Engineering Network (CIREN) database were analyzed to determine the occupant and crash characteristics …
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EXAMINING THE RELATIONSHIPS BETWEEN SHOULDER AND ELBOW SOFT-TISSUE PROPERTIES, THROWING MECHANICS, AND RANGE OF MOTION IN ADULT BASEBALL PITCHERS
… throwing places extremely high loads on soft-tissue structures of the shoulder and elbow, causing pitchers to be injured at an alarming rate. Most researchers believe soft-tissue injuries in pitchers are acute manifestations of chronic microtrauma as a result of repetitive near-maximal …
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Correlating with Local Variation in Collagen Level and Mechanical Properties of the Heart Tissues
<p>The determination of the myocardium's tissue properties is essential in constructing finite element (FE) models of the heart. To obtain accurate results, especially for functionally modeling the heart, we must determine the tissue properties in-vivo. The calculation of the heart tissue …
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Distinct contribution of white matter damage to the clinical syndrome of Alzheimer's disease
… diffusion MRI measures to determine that the tissue properties of WML slightly differed microstructurally between individuals with Alzheimer's disease and non-demented controls, and were strongly related to ventricular enlargement. In order to further understand the role of WML, we factored …
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Development Of An Accurate Benchmarking System For Microwave Breast Imaging
… sensor for the purpose of in vivo dielectric properties measurements. The goal is to provide information for microwave tomography algorithms and phantom development based on in vivo dielectric properties of breast tissues</p> <p>Through the progress of this research two major novel advances …
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Objective Measurement of Peripheral Edema as Symptomatic of Congestive Heart Failure
… is often accompanied by excess fluid buildup in tissue, causing swelling of the extremities, known as peripheral edema. Assessing the severity level of pitting, or indentation, in peripheral edema can potentially provide insights about one's heart condition. When clinicians use digital …
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Non invasive brain stimulation : modeling and experimental analysis of transcranial magnetic stimulations and transcranial DC stimulation as a modality for neuropathology treatment
… and their dependency on coil position, normal tissue anatomy, and the electromagnetic tissue properties.
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Deep Learning-Based Synthesis of Surgical Hyperspectral Images
… and the inability to estimate physiological tissue parameters during interventions. To capture data emanating from underlying physiological tissue properties, hyperspectral imaging (HSI) together with machine learning-based analyses has been proposed as a solution in recent literature. …
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Dynamic Electrical Responses of Biological Cells and Tissue to Low- and High-Frequency Irreversible Electroporation Waveforms
… of microseconds. These pulses permeabilize tissue leading to loss of homeostasis among the cells in the treatment zone. Predicting these treatments is challenging as the electric field (EF) induced through the electrode configuration is heterogeneous and is affected by several adjustable …
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A Nanoindentation Device and the Scale-Dependent Mechanical Properties of Native and Decellularized Liver Tissue
… disease with engineered replacements for cells, tissues, and organs. One technique in regenerative medicine is decellularization, the removal of the native cells from an organ leaving behind an intact structure of extracellular material to act as a scaffold for new cells. Characterizing the …
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Irreversible Electroporation Therapy for the Treatment of Spontaneous Tumors in Cancer Patients
… destruction of cells in a targeted volume of tissue, using brief electric pulses, (~100 µs long) delivered through electrodes placed into or around the targeted region. These electric pulses destabilize the integrity of the cell membrane, resulting in the creation of nanoscale defects that …
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Comparison of passive cervical spine flexion in children and adults
… adult ATD neck, with no consideration for the tissue properties and morphological changes during human development. To help understand the effects of maturation on the changes in neck flexion biomechanics, this study compared the passive cervical spine flexion of children to adults in specific …
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CyberCardia: Patient-specific electrophysiological heart model for assisting left atrium arrhythmia ablation
… electrograms, processes them to extract regional tissue properties, which are used to tune a heart model, creating a patient-specific whole-atrium model. With this model, we can simulate and detect arrhythmia sources, and provide ablation assistance. To build such a system, we investigated the …
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Controlling Tissue Matrix Assembly of Human Mesenchymal Stem Cells toward Engineering Native-like Bone, Cartilage, and Osteochondral Grafts
… defects present special challenges to tissue engineers. An ability to fabricate these tissues in vitro will eliminate clinical complications caused by current techniques used in graft reconstruction. These complications include long-term failure of synthetic grafts, inferior success of …
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Examining viscoelastic response of pregnant rat cervical tissue using 3, 4, and 5 element spring and dashpot models
… of the mechanical behavior of cervical tissue can enable the development of medical devices that can diagnose the condition of cervical insufficiency before labor begins and help avoid preterm birth. In this study, the main focus was to develop a simple viscoelastic model that can be …
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The brain microenvironment and its role in oligodendrocyte progenitor cell ageing
… the ECM biochemical and biophysical properties modulate the ageing OPC phenotype. In my PhD thesis, I aimed to i) characterise biophysical and biochemical changes of the ageing brain tissue, ii) examine how these changes influence the resident OPC regenerative capacity and iii) …
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Ultrasonic imaging methods for quantitative musculoskeletal tissue assessment and improved prosthetic interface design
… of (1) limb geometry and (2) mechanical tissue properties. Toward this goal, we first present the design of a novel multi-modal imaging system for rapidly acquiring volumetric ultrasound imagery of human limbs. Second, we present results of two studies that evaluate the use of ultrasound …
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EFFECTS OF PASSIVE STATIC STRETCHING ON MECHANICAL, NEUROMUSCULAR, AND CARDIOVASCULAR FUNCTION
… factors in modifying muscle and vascular tissue properties. Given the anatomical proximity of these structures, a correlation between the reduction in arterial and joint stiffness following stretching was expected. However, the absence of correlations between these variables suggests that …
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