Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"tissue microarray (TMA)"”.
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Pathologic Markers of Prognosis In Ampullary Carcinoma
… therapy given, and the patient outcomes. A tissue microarray (TMA) of 95 surgically resected ampullary specimens was also constructed to examine whether there is a correlation between classical immunohistochemical profiles for intestinal and pancreaticobiliary tumors and their histologic …
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Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence.
In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) …
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INVASIVE BLADDER CANCER - Aspects on staging and prognosis
… prognostic values of expression profiling and tissue microarray (TMA) in high-risk bladder cancer are investigated in Papers V and VI. Results and conclusions: 1) Diagnostic delay in patients with T1 tumours might have an adverse effect on the prognosis. 2) Treatment delay in patients with …
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Engineering Lipid Nanoparticles for sIRNA Delivery to Silence Identified Targest in Cancer Cells
… <p>Chapter 4 explores prostate cancer using tissue microarray (TMA) analysis to identify stagespecific molecular targets. Through advanced analysis, potential targets are revealed for future RNAi-based therapies, supporting a broader application of siRNA delivery platforms developed …
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Correlation of Caveolin-1 Expression on Tissue Microarray with Prognosis in Renal Cell Carcinoma
PURPOSE: Tissue microarray (TMA) has been utilized for rapid profiling of molecular tumor markers and compares well to results obtained by standard methods. Caveolin-1 is a major structural component of caveolae, which are plasma membrane microdomains implicated in the regulation of intracellular …
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Life Style, Molecular Pathology, and Breast Cancer Risk
… tumour markers were performed using the tissue microarray (TMA) technique. Analyses of dietary habits and tumour characteristics revealed an association between low energy intakes and a more aggressive histopathological phenotype as well as over-expression of the cell cycle regulating …
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Investigation of key non-coding and coding genes in cutaneous melanomagenesis
… from formalin-fixed paraffin-embedded (FFPE) tissues can be obtained that are comparable to those from fresh-frozen samples. The aims of the miRNA project were: first, to identify a melanoma-specific miRNA expression profile; secondly, to investigate roles of some of the melanoma-specific …
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Genetic markers in circulating tumour cells as a measure of the metastatic propensity of uveal melanoma
… immunomagnetic capture of UM CTCs. A tissue microarray (TMA) was created from 1mm cores taken from archived primary UM tissue. Normal tissue and cutaneous melanoma were added as controls. The TMA was stained by immunohistochemistry (IHC) for melanoma, melanocyte, and stem cell markers. …
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Label-free breast histopathology using quantitative phase imaging
… on manual microscopic examination of stained tissue. Being qualitative and manual in nature, this standard diagnostic procedure can suffer from inter-observer variation and low-throughput. In addition, stain variation between different samples and different laboratories creates problems for …
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Immune Infiltrates in Breast Cancer: Clinical Significance from Histopathology to Prognosis
… Breast Cancer Association Consortium’s (BCAC) tissue microarray (TMA) dataset. TMAs are cassettes designed to efficiently organise cylindrical tumour samples (cores) from a large number of patients, and stain their horizontal sections for a variety of targets. BCAC’s TMA dataset is composed of …