Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"tissue culture model"”.
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Investigating the by-stander effect of Hypericin induced photodynamic therapy on human skin cells
… (Mc) and fibroblasts (Fb) in an in vitro tissue culture model thus representing both the epidermal and dermal cellular compartments of human skin.
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Herpes Simplex Virus Glycoprotein D/Host Cell Surface Interaction Stimulates <em>Chlamydia trachomatis</em> Persistence via a Novel Pathway.
… and a decrease in infectious progeny. Several models of chlamydial persistence have been described, including interferon-γ (IFN-γ), IFN-α, IFN-β, and tumor necrosis factor-α-exposure and nutrient deprivation. Previously, we established an <em>in vitro</em> co-infection model of two of the most …
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Identification of host factors required for cytosol entry by Shigella flexneri: Results of a genome-wide CRISPR/Cas9 screen
… genome-wide CRISPR/Cas9 knockout screen using a tissue culture model of epithelial cell infection. I used a hierarchical validation method which combined arrayed high-content microscopy and semi-automated image analysis to confirm a novel set of host factors which facilitate *Shigella* infection. …
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Investigating Human Cell Influence on the Micromechanical Environment of a 3D-Printed Bone Tissue Model
… cells to form pre-metastatic niches, infiltrate tissue systems, and promote survival. Current models, such as 2D in vitro cell culture and preclinical animal models, fail to replicate the physiological metastatic bone environment, leading to high failure rates of anti-cancer drugs and limited …
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Host specific gene expression of the baculovirus, Spodoptera frugiperda nuclear polyhedrosis virus, in insect cell lines
… infection. Our laboratory has developed three tissue culture model systems to study host specificity. This research focuses on System II, developed by Carpenter and Bilimoria, in which Spodoptera fingiperda nuclear polyhedrosis virus (Sf MNPV) permissively infects Si fiiigiperda IPLB-21 (SF …
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Lesioni degenerative e meccanismi di riparo della superficie oculare: lo pterigio e le deficienze delle cellule staminali del limbo (LSCD). Studio immunoistochimico e tecniche di coltura cellulare
… angiogenesis and extracellular matrix remodeling. The Angiotensin converting enzyme (ACE or ACE I) is the major component of the Renin-angiotensin system (RAS) converting the inactive decapeptide Angiotensin I (Ang I) to the active octapeptide Angiotensin II (Ang II). Besides this …
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St John's Wort photomedicine for Melonoma
… of melanoma cells to hypericinPDT in an in vitro tissue culture model. This investigation was three-fold. Firstly, the susceptibility of melanoma cells to the treatment was determined using cell viability assays. We found a dose of 3 µM light-activated hypericin was effective in reducing cell …