Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 34 for “"timekeeping"”.
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Metabolic Regulation of Circadian Timekeeping
… of primary carbohydrate metabolism to cellular timekeeping, with particular emphasis on the pentose phosphate pathway. I also describe and validate a new 13C labelling technique for accurate determination of the relative flux through early primary metabolic pathways. This is accompanied by the …
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Timekeeping and accelerometry with robust light pulse atom interferometers
… sensitivity to these inhomogeneities. For atomic timekeeping applications, a Ramsey LPAI sequence based on stimulated Raman transitions and frequency-swept adiabatic rapid passage (ARP) was developed. Raman ARP drives coherent transfer in an effective two-level atomic system by sweeping the Raman …
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Sensing and timekeeping using a light-trapping diamond waveguide
Solid-state quantum systems have emerged as promising sensing platforms. In particular, the spin properties of nitrogen vacancy (NV) color centers in diamond make them outstanding sensors of magnetic fields, electric fields, and temperature under ambient conditions. This thesis focuses on …
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Circadian Timekeeping of Body Temperature by the Mammalian Suprachiasmatic Nucleus
The circadian rhythm of body temperature (CRT) is a universal cue for entraining the peripheral clocks in mammals. The hypothalamic suprachiasmatic nucleus (SCN) is required for generating the ~24-hour rhythms of body temperature (Tb); however, the neural mechanism underlying this regulation …
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Stability enhancement of atomic timekeeping using Raman adiabatic rapid passage
… expand the range of applications for precision timekeeping, and enable cheaper implementation of existing applications. This type of clock may be realized by use of optical Raman interferometry based on pulsed interrogation of cold atoms. However, this method suffers from serious systematic …
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Molecular and Genetic Analysis of Neuropeptide Signalling in Mammalian Circadian Timekeeping
… roles for the VIP and VPAC2 neurons in circadian timekeeping.
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Tools for mindful timekeeping : 4 devices to change our relationship to time
… being. Time pressure comes from the networks of timekeeping that surround us. It's not just our clocks and watches. Time is synchronized across devices, cities, and continents. Networked time regulates our lives today more than ever before. Modern timekeeping has shaped our culture into one that …
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Unequal Hours: The Jewish Reception Of Timekeeping Technology From The Bible To The Twentieth Century
… such change often took place quite slowly. Timekeeping technology has been in development for more than 3,500 years; by examining the long Jewish relationship to timekeeping, this dissertation is intended to serve as proof-of-concept for how historians of Judaism and historians of technology …
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Examining the Acute and Chronic Effects of Sepsis on the Circadian Clock in the Mouse
… are driven primarily by an endogenous biological timekeeping system, with the master pacemaker located in the suprachiasmatic nucleus. Studies have indicated bidirectional relationships between the circadian and the immune systems, however while there is much evidence regarding the regulation of …
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Using Translational Switching to Investigate the SCN Clockwork
… that adapt mammals to environmental cycles. Timekeeping in the SCN is underpinned by a self-sustaining cell-autonomous transcriptional/translational delayed feedback loop (TTFL), whereby negative regulators inhibit their own transcription. The positive regulators CLOCK and BMAL drive …
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Connecting the Circadian Clock with Chemosensation
… e.g., light-dark cycle. A resettable timekeeping mechanism called the circadian clock internally drives these cyclical changes with a ~24 hour period. Using electrophysiological, behavioral and molecular analyses, I tested where and how these two conserved processes, viz., the …
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Circadian Regulation of Protein Homeostasis
… differing demands of day and night. Circadian timekeeping has a cell-autonomous basis, amenable to study in cultured mammalian cells, where daily rhythms have been shown to affect most biological processes. In various models, rhythms in protein abundance of 10-20% of the proteome have been …
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Circadian Orchestration of the Cellular Proteome
… of a core set of ‘clock proteins’. This cellular timekeeping system is remarkably precise and robust to perturbations. In the first chapter of this thesis I explored the mechanism of action of picrotoxin, a drug that shortens circadian period through unknown means. I uncovered features that are …
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Frequency stability in a compact, deployable optical atomic clock
… in this thesis to transfer optical atomic timekeeping technology from the laboratory to the field and to improve analytic tools for spectroscopy with ultra-narrow lasers are motivated by a need to support GPS-denied operations (a DARPA objective) and to enable a broad range of positioning, …
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Reading Intervention Using Interactive Metronome Treatment
… that guided this study focused on how internal timekeeping affects reading fluency. This study used a multiple baseline across participant’s single-subject design. Three participants were monitored to determine a baseline using Curriculum Based Measures and Correct Word Per Minute data, and then …
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Remote synchronization method for the quasi-zenith satellite system
This dissertation presents a novel satellite timekeeping system which does not require on-board atomic clocks as used by existing navigation satellite systems such as GPS, GLONASS or the planned GALILEO system. This concept is differentiated by the employment of a synchronization framework combined …
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Orchestral Conducting in Virtual Reality
… infers fundamental conducting gestures, such as timekeeping and accent signaling, with the use of carefully fine-tuned parameters. In turn, VRC adjusts the orchestra’s produced sound, modeling a real-life orchestra’s response as best as possible. VRC is designed to encourage good conducting …
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Circadian Disruption by Light at Night: Implications for Mood
… shift work. LAN may disrupt physiological timekeeping, leading to dysregulation of internal processes and misalignment between behavior and the environment. Recent evidence suggests that individuals exposed to excessive LAN, such as night shift workers, have increased risk for depressive …
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Terahertz frequency synthesis in CMOS for a chip-scale molecular clock
… electronics could enable low-cost, atomic-grade timekeeping for applications that are poorly served by existing clock technologies. However, the first CSMC left opportunities to optimize the terahertz electronics for a second version, for instance by improving transmitter phase noise. In this …
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Mathematical modelling of the light input signalling pathways to the Arabidopsis circadian oscillators
… of how light inputs structure circadian timekeeping in Arabidopsis.
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