Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"time-resolved cryo-EM"”.
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Methods for time-resolved cryo-EM using pulsed infrared radiation and vapour phase deposition
Electron cryo-microscopy (cryo-EM) is an imaging technique for determining high spatial resolution structures of proteins. Technological advances have made it possible to attain atomic resolution and attention may now be directed towards the challenge of extending the time resolution of cryo-EM …
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Investigating the Molecular Mechanism of Ribosome Recycling
… synthesis that ensures ribosomal subunits remain available for new rounds of translation, has been largely overlooked. Despite being essential to the survival of the cell, several mechanistic aspects of ribosome recycling remain unclear. Aminoglycosides are a class of antibiotics that bind …
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Structural insights into the GABAA receptor gating cycle
… within the vertebrate central nervous system. They activate and desensitize in a few milliseconds, which is a crucial requirement for accurate synaptic signalling. Such fast conformational transitions, however, have proven impervious to investigation via conventional structural biology …