Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"tight skin"”.
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Genetic Exploration of Hereditary Immune Diseases
… alterations, and v</p> <p>autoantibodies. The tight skin 2 (Tsk2/+) mouse model of SSc demonstrates signs similar to SSc including tight skin and excessive deposition of dermal ECM proteins. Our hypothesis is that ENU caused single nucleotide mutations in one or more genes in the Tsk2/+ locus …
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Expression and regulation of monocyte chemoattractant protein-3 (MCP-3) in fibrosis
… connective tissue disease characterised by skin thickening and widespread, but variable, visceral fibrosis. The aetiopathogenesis is likely to involve immunological activation and microvascular dysfunction leading to excessive accumulation of extracellular matrix (ECM) with increased …