Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"thyroiditis"”.
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The role of the HLA region in Hashimoto’s Thyroiditis
Hashimoto’s Thyroiditis is an autoimmune disease of the thyroid gland characterised by thyrocyte death. Although it was previously thought that Hashimoto’s thyroiditis shared common aetiology with Graves’ disease, there is now significant evidence to suggest separate causal loci. The aims of this …
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Clinical Analysis and Review of Literature Associated with Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT), named after its discoverer Hakaru Hashimoto, is a chronic autoimmune inflammatory disease. HT develops when an autoimmune response causes inflammation of the thyroid gland that ultimately leads to the destruction of thyroid tissue, effectively killing the organ. An …
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The Life Story Analysis of Those Suffering from Autoimmune Thyroiditis
… understand the pervasive impacts of autoimmune thyroiditis, specifically Hashimoto’s and Graves’ disease. To accomplish this, the life story methodology was utilized to gather individual experiences from 11 participants diagnosed with Hashimoto’s or Graves’ disease. The participants completed a …
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Aberrant Communication and Protein Kinase C in Experimental Autoimmune Thyroiditis
… to the pathogenesis of induced autoimmune thyroiditis in Lewis rats. Our hypothesis was; inflammation-induced lymphocytic infiltration and subsequent fibrosis results in physical disruption of gap junctional communication in the target tissue contributing to the disease process. Our study …
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Examining autoimmune sequelae during cancer immunotherapy in a combined autoimmune thyroiditis and tumor mouse model
… of autoimmune sequelae, including autoimmune thyroiditis. It has been suggested that the immunotherapy resulted in an alteration in the immunoregulatory mechanism(s). Using experimental autoimmune thyroiditis (EAT), a mouse model of Hashimoto's thyroiditis (HT), the importance of regulatory T …
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Einfluß einer Selen-Substitution auf den Verlauf einer Autoimmunthyreoiditis
… Supplementation in Patients with Autoimmue Thyroiditis Decreases Thyroid Peroxidase Antibodies Concentrations ROLAND GÄRTNER, BARBARA C. H. GASNIER, JOHANNES W. DIETRICH, BJARNE KREBS, AND MATTHIAS W. A. ANGSTWURM Departement of Endocrinology, Medizinische Klinik Innenstadt, University of …
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Diseased Thyrocytes Have Aberrant Communication and TNF Receptor Secretion
… (TNF- α).</p> <p>We have used thyroiditis as our model of autoimmunity and have documented the development of spontaneous thyroiditis in MRL-lpr/lpr mice. We have found aberrant connexin expression in thyroid tissue from these mice. The abnormal gap junction assembly persisted …
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Molecular Insights of Primary Thyroid B-cell Lymphomas by Somatic Genetic and Immunogenetic Profiling
… derived from a background of Hashimoto’s thyroiditis and comprise largely of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (EMZL) and diffuse large B-cell lymphoma (DLBCL), followed by follicular lymphoma (FL). The Du group has previously shown that thyroid EMZL …
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Der humane Natrium-Jodid-Symporter (hNIS) : Entwicklung einer Methode zur Quantifizierung der hNIS-mRNA-Expression und Analyse der Rolle als Antigen bei autoimmunen Schilddrüsenerkrankungen
… of patients with Graves’ disease and Hashimoto’s thyroiditis. For that purpose the "full length"-hNIS was cloned from cDNA of thyrocytes and its functional activity was examined after transfection into CHO cells. After the synthesis of hNIS through an in vitro transcription/translation system, …
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Immunological mechanisms controlling chronic inflammatory diseases
… of the thyroid in a mouse model of spontaneous thyroiditis. TAZ10 transgenic mice express a human T cell receptor (TCR) specific for a cryptic epitope of thyroid peroxidise (TPO) generated upon endogenous processing by thyroid epithelial cells (TEC), and a naturally occurring antagonistic …
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Gibt es einen Zusammenhang zwischen Major Depression und Autoimmunthyreoidits oder anderen Erkrankungen der Schilddrüse?
In der vorliegenden Arbeit wurde der Zusammenhang zwischen Patienten mit Major Depression nach DSM-IV und Schilddrüsenerkrankungen, unter besonderer Berücksichtigung einer Autoimmunthyreoiditis, untersucht.In einem Zeitraum von 14 Monaten wurden prospektiv 100 Patienten in die Studie …
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Relación entre la presencia de tiroiditis linfocítica con la gravedad y recurrencia/persistencia del carcinoma diferenciado de tiroides.
Introducción: Para el sistema endocrino la neoplasia más frecuente es el cáncer diferenciado de tiroides, con un claro incremento en su incidencia. Es importante encontrar asociaciones que posteriormente permitan establecer factores de riesgo y/o protectores claves en la estrategia terapéutica …
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Ancestralidade como fator de risco para hipotireoidismo: estudo da coorte ELSA-BRASIL
Introduction– Genomic ancestry refers to the genetic relationship between an individual and their ancestors, from whom they biologically descend. The self-reported ancestry of the Brazilian population is subject to important genomic divergence and there are sensitive markers capable of stratifying …