Global ETD Search
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Showing 1 to 2 of 2 for “"thymine starvation"”.
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The role of recombinational repair in the mechanism of killing during thymine starvation in Escherichia coli
Thymineless death (TLD) describes a universal phenomenon in which cells cannot recover after starvation for one of the four DNA precursors, dTTP. The mechanism of how cells lose viability during thymine starvation has remained a mystery for decades. In Escherichia coli, thymine-starved cells were …
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The in Vivo Roles of the RdgB Enzyme in Escherichia Coli and the Detection of Rare Non-Canonical DNA Precursors
Adenine, guanine, cytosine, and thymine deoxyribonucleotides make up the pool of canonical DNA precursors in living organisms. The incorporation of non-canonical DNA precursors into DNA during replication can lead to mutagenesis, chromosomal damage, or both. The approach taken by living organisms …