Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 81 for “"thymine"”.
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Thymine Deprivation in Lysogenic Bacillus Megaterium
Made available in DSpace on 2014-12-09T22:04:16Z (GMT). No. of bitstreams: 1 6711882.pdf: 10200673 bytes, checksum: 270d26e2698812b9d7cbbd96f8c90600 (MD5) Previous issue date: 1967
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Study of Electron-Impact Induced Fragmentation of Thymine
… this thesis was to generate a molecular beam of thymine and to investigate the fragmentation processes induced by low-energy electron impact. A molecular beam of thymine is generated by placing thymine in powder form inside a resistively heated oven. The beam of thymine is then crossed by a …
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Dynamics of UV -Excited Uracil, Thymine, and Cytosine
… these dimers form. The pyrimidine bases (uracil, thymine, and cytosine) have been studied with ab initio multiple spawning molecular dynamics and high level electronic structure methods. This work has involved both gas-phase and aqueous dynamics as well as simulation of the time-resolved …
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Studies of the inactivation of thymine hydroxylase by 5-ethynyluracil
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1997.
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Synthesis and characterization of bis-MPA based branched polymers with thymine core
… bis-MPA based branched materials was performed. Thymine derivative was incorporated into the polymer structure as a core moiety and an active centre for H-bonding. The formation of assemblies was investigated.
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The Synthesis of Ribonucleic Acid by a Thymine Requiring Strain of Escherichia Coli
Made available in DSpace on 2014-12-05T21:45:36Z (GMT). No. of bitstreams: 1 6200593.pdf: 4186094 bytes, checksum: 7d1297c786d90dd1a721c24254e47a21 (MD5) Previous issue date: 1961
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The role of recombinational repair in the mechanism of killing during thymine starvation in Escherichia coli
Thymineless death (TLD) describes a universal phenomenon in which cells cannot recover after starvation for one of the four DNA precursors, dTTP. The mechanism of how cells lose viability during thymine starvation has remained a mystery for decades. In Escherichia coli, thymine-starved cells were …
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Fundamentals of Excess Electron Transport in Biologically Relevant Systems
Thymine dimers are premutagenic lesions that form via ultraviolet irradiation of DNA. While the distribution of thymine dimers is non-random, it is also not yet predictable. Thymine dimer accumulation is likely to be controlled by both its formation and reversion. Formation of thymine dimers occurs …
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INFLAMMATION INDUCED CYTOSINE DEAMINATION DAMAGE IN CANCER ETIOLOGY
… of human cancer is dominated by cytosine to thymine transition mutations, and the primary mechanism for these mutations is the deamination of cytosine and cytosine analogs to uracil and the corresponding uracil analogs. During replication, uracil and uracil analogs codes as thymine, leading …
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Hapten inhibition studies assessing the ability of a thymine derived hapten to bind DNA antibodies in sera from patients with systemic lupus erythematosus (SLE)
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The Utility of 7-Deazaguanine: Part I. High Affinity, High Fidelity Modules for Supramolecular Chemistry, And, Part II. Molecular Recognition of Uracil and Thymine
… evaluated as a molecular recognition unit to a thymine (T) bulge of a short 10-bp oligomer. The ligand was found to stabilize the T bulge quite significantly (+7.8°C) relative to the C bulge (3.6°C) and A and G bulges (≤ 2.0°C) at 5.0 equivalents, when the bulged base was flanked …
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High harmonic generation and attosecond dynamics in small organic molecules and biomolecules
… relevant molecules: the nucleobases uracil and thymine, and the radiosensitiser molecule 5-fluorouracil. We firstly compare differences in ionization and HHG between the two nucleobases, and between different molecular orientations relative to the laser polarization direction. On average we …
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Synthesis and characterization of ammonium ionenes containing hydrogen bonding functionalities
… using DNA nucleobase pairs such as adenine and thymine. Novel adenine and thymine functionalized segmented and non-segmented ammonium ionenes were successfully synthesized using Michael addition chemistry. In non-segmented systems, we investigated the influence of spacer length on …
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Characterization of four members of the ferrous ion and Ü-ketoglutarate dependent hydroxylase family from Trypanosoma brucei : two thymine hydroxylase-like protens, J-binding protein 1, and an ALKB homolog
Thesis (Ph. D.)--Michigan State University. Biochemistry and Molecular Biology, 2010
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Mg- and Zn-Mediated Synthesis of Heterocycles in Solution and on the Solid Phase
… high functional group tolerance. Thus various thymine derivatives have been prepared both in solution and on the solid phase. Alternatively, a new route to functionalized heterocyclic Grignard reagents was developed using a low-temperature halogen-magnesium exchange. Ester, amide and nitrile …
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Electron Attachment To Small Molecular Clusters
… pyridine (prototype of biological molecule) and thymine (one of the DNA nucleobases), both in gas-phase and surrounded by water (forming small clusters). We provide a comparison of pyridine and pyridine-H<sub>2</sub>O calculations for various standard scattering models (Static Exchange, Static …
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The in Vivo Roles of the RdgB Enzyme in Escherichia Coli and the Detection of Rare Non-Canonical DNA Precursors
Adenine, guanine, cytosine, and thymine deoxyribonucleotides make up the pool of canonical DNA precursors in living organisms. The incorporation of non-canonical DNA precursors into DNA during replication can lead to mutagenesis, chromosomal damage, or both. The approach taken by living organisms …
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Synthesis and Characterization of Cation-Containing and Hydrogen Bonding Supramolecular Polymers
… heterocyclic DNA nucleobases such as adenine, thymine and uracil. Our investigations in this field have focused on the use of DNA nucleobase pair interactions to control polymer self-assembly and rheological behavior. Novel acrylic adenine- and thymine-containing monomers were synthesized from …
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