Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"throughput measurement"”.
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High throughput measurement of antibody and complement mediated immunity to meningococcal disease
… <br></br><br></br> In this study a high throughput antibody-mediated complement deposition assay has been developed to measure the deposition of both C3b/iC3b and C5b-9 onto <i>Neisseria meningitidis</i>. Antibody mediated C5b-9 deposition measured in this assay has been shown to …
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High throughput measurement and perturbation of tissues and tissue-derived cellular models
Human tissues are composed of trillions of cells whose states and interactions drive health and disease. Deciphering which cells and interactions are associated with any given disease is challenging due to the vast complexity of a tissue. Successfully doing so requires a suite of tools for …
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P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism
… Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.
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An instrument for high-throughput measurements of fiber mechanical properties
… The instrument is intended to provide high throughput measurement of single fiber geometric properties, tensile properties, elastic properties, surface roughness properties, friction properties, bending properties, and torsion properties. The instrument is capable of performing all of these …
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Analysis and dynamic modelling of complex systems
… advent of rapid genome sequencing and other high throughput measurement techniques, the biological sciences are<br>entering an unprecedented age of discovery. Biology is faced with a lot of facts that need an explanation. But while physics uses mathematics to represent the laws of nature, biology …
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Throughput Measurements and Empirical Prediction Models for IEEE 802.11b Wireless LAN (WLAN) Installations
… a method of predicting the expected wireless LAN throughput using a site-specific model of an indoor environment. In order to develop this throughput prediction model, two wireless LAN throughput measurement products, LANFielder and SiteSpy, were created. These two products, which are patent …
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High precision mass-based assay to examine growth regulation of the cell cycle
… to be a fundamental property of cell state, its measurement on a single-cell basis with high-resolution has been elusive primarily due to enormous experimental barriers. This thesis discusses the use of a cantilever based suspended microchannel resonator (SMR) to measure mass, and resistive pulse …
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Containerless measurement and thermodynamic prediction of the physical properties of liquid steels
… iron lattice. Additionally, direct experimental measurement of these properties is hindered by the requisite high temperature, high reactivity of the melt, and the vast composition space of steel alloys. Herein, both the experimental and modelling challenges are introduced and addressed. An …
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Model-Based Genomic/Proteomic Signal Processing in Cancer Diagnosis and Prediction
In recent years, high throughput measurement technologies (gene microarray, protein mass spectrum) have made it possible to simultaneously monitor the expression of thousands of genes or proteins. A topic of great interest is to study the difference of gene/protein expressions between normal and …
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Microfluidic concentration-enhanced single cell enzyme activity assay
… size scale which enables high sensitivity, high throughput measurements. In this thesis we develop a microfluidic platform for the direct measurement of enzyme activities from selected single cells without disrupting their extracellular context. We develop modules to: enhance enzyme assay …
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A Simulator for analyzing the throughput of IEEE 802.11b Wireless LAN Systems
… a simulator which will predict the performance (throughput) of an end user. The throughput is predicted for a given topology and traffic source. The simulator is built on object oriented design. To validate the simulator a measurement campaign was conducted. The campaign was conducted in two …
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Trust-aware virtual network embedding algorithms for wireless sensor networks
… and security and enhance the average network throughput, measurement error efficiency, and processing time when the trust attributes are assigned, making the VNE algorithm more practical. Since centralized algorithms suffer from scalability issues, in the second objective, we design a novel …
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Computational modeling techniques for biological network productivity increases : optimization and rate-limiting reaction detection
The rapid development and applications of high throughput measurement techniques bring the biological sciences into a 'big data' era. The vast available data for enzyme and metabolite concentrations, fluxes, and kinetics under normal or perturbed conditions in biological networks provide …
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Applying integrative computational models to study the evolution of gene regulation
… and biological processes. The advance of high-throughput measurement technology, such as microarray and next-generation sequencing, enabled us to globally scrutinize various cell properties related to gene regulation and build statistical models to make quantitative predictions. The …
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Identifying protein complexes and disease genes from biomolecular networks
With advances in high-throughput measurement techniques, large-scale biological data, such as protein-protein interaction (PPI) data, gene expression data, gene-disease association data, cellular pathway data, and so on, have been and will continue to be produced. Those data contain insightful …
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High-throughput sensing of bulk fluids and freely flowing particles with opto-mechano-fluidics
… in detection speed as well. Fast non-contact measurement is made possible with a hollow type of MEMS device, which weighs bio-analytes in real-time as they flow through the internal channel of the device (Nat Commun 6:7070, 2015). However, the fastest achieved detection speed is still less …