Global ETD Search
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Showing 1 to 3 of 3 for “"thrombospondins"”.
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Mechanisms Mediating Adaptive Presynaptic Muting Induction
… but not instructive, for silencing induction. Thrombospondins were identified as the astrocyte-derived factors responsible for muting competence in neurons, and they act through binding to the a2d-1 subunit of voltage-gated calcium channels. cAMP-activated protein kinase A exhibited …
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Innate Immune Transcription Activator Interferon Regulatory Factor-3 (IRF3) Contributes to Maladaptive Remodeling Post-myocardial Infarction
… border zone by upregulating the expression of thrombospondins. I have shown that IRF3 deficiency, which liberates endogenous anti-angiogenic signals, promotes angiogenesis following ischemic injury. These data suggest that IRF3 is a potent regulator of cardiac remodeling and may be an effective …
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Untersuchungen zur antiangiogenen Aktivität des matrizellulären Proteins Thrombospondin-2
Die Bildung neuer Gefäße durch Tumoren (Tumorangiogenese) ist ein wichtiger Mechanismus für das Wachstum und die Progression von Tumorgewebe. Tumorangiogenese ist von einem komplexen Zusammenspiel von pro- und antiangiogenen Faktoren abhängig. Thrombospondin-2 (TSP-2) gehört zu den endogenen …