Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"thrombolysis"”.
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Repeated full dose thrombolysis in patients hospitalised with myocardial infarction : safety and efficacy
The treatment and outcome myocardial infarction has been revolutionised by the demonstration that thrombolytic grugs can open the infarct-related arterty, salvage ischaemic myocardium, preserve left ventricular function and save lives. However, thrombolytic drugs are not uniformly effective in …
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Early outcomes of thrombolysis for acute ischaemic stroke in a South African tertiary care centre
… Recombinant tissue plasminogen activator (tPA) thrombolysis is effective in treating acute ischaemic stroke, but may not be a viable option in developing countries. This prospective observational study was designed to assess the short-termoutcomes and safety of tPA for the treatment of stroke at …
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An exploratory inquiry into the implementation of prehospital thrombolysis in the treatment of acute myocardial infarction : a case study of a private emergency medical service within South Africa
Dissertation submitted in fulfilment of the requirements for the degree of Master of Health Sciences: Emergency Medical Care, Durban University of Technology, Durban, South Africa, 2019.
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Venous Thrombosis: Formation, Evolution And Resolution Imaging Using Non-Invasive MRI Techniques
… thrombus rich in fibrin has better response to thrombolysis than red cell rich (acute phase) or collagen rich (chronic) thrombus.Thus, there is a need for a diagnostic technique that provides better information on the stage of<br/>thrombus organization in-vivo and allows identification of …
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A cross-sectional study of ECG patterns and outcomes of patients thrombolysed for ST-elevation myocardial infarction at a district, public Cape Town hospital
… of stay and the various timings surrounding thrombolysis were presented using proportions, mean and standard deviation. Assumptions were tested using the X2 - test or Fishers Exact test. A p-value less than 0.05 was considered significant. Results The study enrolled 104 patients of which 25 …
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Treatment of brain cancer and ischaemic stroke utilising High Intensity Focus Ultrasound (HIFU) guide with MRI
… the brain. A HIFU system was also used to assist thrombolysis in cooperation with a thrombolytic drug such as recombinant tissue plasminogen activator (rt-PA) in vitro and in vivo. It was shown that higher intensity results to higher volume of dissolved clot, but there is a limit of the intensity …
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Nematomi insulto simptomai /
… is a lack of data and studies on the use of thrombolysis in patients with symptoms other than NIHSS. More targeted research on this topic is needed before detailed recommendations can be made. Key terms: NIHSS, mRS, minor stroke, stroke symptoms, stroke thrombolysis.
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Prevalence of Occlusive Myocardial Infarction (OMI) in patients diagnosed with Non-ST-Elevation Myocardial Infarction (NSTEMI) at a single private facility in Cape Town, South Africa, during 2019
… results, the proportion undergoing angiography, Thrombolysis in Myocardial Infarction (TIMI) flow grades, and door-to-angiogram times. Methods: A cross-sectional, observational study was conducted using a retrospective chart review of NSTEMI patients who underwent angiography. Data were analysed …
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Prevalence of Occlusive Myocardial Infarction (OMI) in patients diagnosed with Non-ST-Elevation Myocardial Infarction (NSTEMI) at a single private facility in Cape Town, South Africa, during 2019
… results, the proportion undergoing angiography, Thrombolysis in Myocardial Infarction (TIMI) flow grades, and door-to-angiogram times. Methods: A cross-sectional, observational study was conducted using a retrospective chart review of NSTEMI patients who underwent angiography. Data were analysed …
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Aspiration Thrombectomy as the Sole Treatment for Acute and Sub-acute Deep Venous Thrombosis (DVT) of the Lower Extremity: mid and long-term clinical results
… separated from the clot was measured. Adjuvant thrombolysis with urokinase was performed when the aspirated blood was over 400 ml or when the aspiration thrombectomy was incomplete. Results: Anatomical success was achieved in 92/108 (85%) patients after aspiration thrombectomy treatment of the …
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Longer term neurocognitive outcomes after acquired brain injury
… ischemic stroke have focused on the effect of thrombolysis (IVT) and thrombectomy (EVT) on survival and functional outcomes. Little is known about the cognitive outcomes after IVT and EVT following acute ischemic stroke. The objective of this systematic review was to determine the differential …
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Novel Tools for Interventional Magnetic Resonance Imaging
… angioplasty procedures and also for mechanical thrombolysis. Flow phantoms, Thiel soft-embalmed human cadavers with partially re-established perfusion and a porcine model were used for in vitro, ex vivo and in vivo validation, respectively.<br/><br/>The results demonstrate that these …
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Barriers to acute stroke care at a tertiary hospital in the Western Cape
… hours for those patients that arrived within the thrombolysis time window. Only 21 of 50 patients were referred and assessed by the stroke unit team. Only 3 of the 21 patients received intravenous thrombolysis and none received mechanical thrombectomy. Conclusion: There majority of the patients …
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Effect of time horizon on incremental cost-effectiveness ratios
… survival data from a published trial evaluating thrombolysis in patients with myocardial infarction and applied this methodology over different time horizons.
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A comparison of machine learning methods for risk stratification after acute coronary syndrome
… risk stratification are risk scores such as the Thrombolysis in Myocardial Infarction (TIMI) score and Global Registry of Acute Coronary Events (GRACE) score. However, prior work has shown that many patients who are not traditionally defined as high-risk by the TIMI or GRACE scores suffer adverse …
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An evaluation of cardiac services in four hospitals in Lancashire for patients with ischaemic heart disease
… at hospital 'door' to receiving intra-venous thrombolysis 'needle') time questionable; 2) A high proportion (67%) of re-infarction hospital deaths were associated with the use of CA 2 channel blocking drugs (given in spite of adverse clinical consensus); 3) 52% of patients diagnosed with Left …
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Outcomes of mechanical thrombectomy at a single-centre tertiary level public health care hospital in South Africa
… Stroke Programme Early CT score was 8. Bridging thrombolysis was given to 65% of participants. Median time from symptom onset to reperfusion was 339 minutes. Successful recanalization (mTICI 2b/3) was obtained in 62%. At 90 days, 34 % of participants reached functional independence and mortality …
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Comparison of Aspiration Thrombectomy with Glycoprotein IIb/IIIa Inhibitor versus Aspiration Thrombectomy Alone in Primary Percutaneous Coronary Intervention
… 정의하였고 두 군 간의 임상적소견과 관상동맥조영술에서의 스텐트 시술 전 후 Thrombolysis In Myocardial Infarction (TIMI) 혈류와 TIMI myocardial perfusion (TMP) 등급을 비교하였다. TIMI 혈류 0,1,2는 no reflow로, TIMI 혈류 3는 정상 혈류로 정의하였다. 결과 : 환자의 나이는 II군에서 더 많았으며(53 ±11 vs. 58 ±12세, p=0.014), 좌심실구혈율은 I군 에서 더 낮았다(48±11 vs. 53±11%, p=0.004). …
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Optimizing Equity in Healthcare Access: An Integer Programming Approach to Emergency Department Closures and Travel Burden Disparities in Ontario
… magnetic resonance imaging, acute stroke thrombolysis centres, endovascular therapy centres, and intensive care units were also calculated. For historical closure data, travel burden for the closest DAs was calculated. A simulation then hypothetically closed all rural EDs one at a time, …
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Occluson Pattern in Circle of Willis: Prognostic Marker for Endovascular Treatment in Acute Carotid Terminus Occlusion
… was achieved higher in MCA-only group [Thrombolysis in Cerebral infarction (TICI) classification 2b–3 14/33 (42.4%) vs. 3/21 (14.3%), p=0.030]. Patients in MCA only group had significantly better prognosis than MCA-plus (p=0.001). The MCA plus was proven as an independent predictor for …
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