Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"thromboembolic"”.
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Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension in Cape Town, South Africa
… and potentially curative therapy for chronic thromboembolic pulmonary hypertension (CTEPH), associated with impressive improvements in symptoms and haemodynamics. However, it is only offered at a few centres in South Africa. The characteristics and outcomes of patients undergoing PEA in Cape …
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Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension in Cape Town, South Africa
… and potentially curative therapy for chronic thromboembolic pulmonary hypertension (CTEPH), associated with impressive improvements in symptoms and haemodynamics. However, it is only offered at a few centres in South Africa. The characteristics and outcomes of patients undergoing PEA in Cape …
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A genome-wide association study in chronic thromboembolic pulmonary hypertension and the ADAMTS13-VWF axis
Chronic thromboembolic pulmonary hypertension (CTEPH) is an important and severe consequence of pulmonary embolism (PE), resulting from failure of thrombus resolution. Identifying genetic risk factors for CTEPH would provide important insights into pathobiology and might allow risk-stratification …
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Application of passive flow control to mitigate the thromboembolic potential of bileaflet mechanical heart valves: an in-vitro study
… (BMHV) continues to be associated with risk of thromboembolic complications despite anti-coagulation therapy. Mechanical heart valves have been the gold standard in valve heart replacement since the 1950s with BMHVs currently still being the valve of choice for younger patients. Given that a …
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Clinical and Prognostic Characteristics of Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH) /// Клинични и прогностични характеристики на пациенти с хронична посттромбоемболична пулмонална хипертония (СТЕРН)
СТЕРН е опасно за живота състояние, при което организирани тромбоемболични маси в белодробните съдове водят до повишено белодробно съдово съпротивление (PVR), прогресивна ПХ и десностранна сърдечна недостатъчност. СТЕРН е свързана със значима заболеваемост и смъртност, ако не се лекува …
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An Experimental Method of Detection of Venus Thrombosis in the Lower Extremities of Dogs
For many years pulmonary embolism and tho thromboembolic phenomenon has avidly hold the interest of many of those connected with tho field of medicine. Once the signs anti symptoms of thromboembolic disease become manifest, the diagnosis of such an entity is not seemingly difficult, however, the …
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Mechanische Thromboseprophylaxe bei Hüft-Endoprothesen : prospektive Studie zum Einsatz des Venaflow-Gerätes
… a total hip replacement, have higher risk for thromboembolic complications. Using current regimes of prophylaxis the probability for a deep vein thrombosis (dvt) amount to 3-15%. In this prospective, randomised study we explore the benefit of the additional use of a venous calf pump (Venaflow). …
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Multimodal Imaging of Inflammation at the Neurovascular Interface in Cerebrovascular Disease
… (so-called “vulnerable plaques”) that trigger thromboembolic stroke. While conventional clinical imaging simply measures the degree of vessel stenosis, it is a crude measure that reveals little of the metabolic processes affecting plaque vulnerability. Our research demonstrates the utility of …
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Four-Dimensional Cardiac Magnetic Resonance Analysis in Patients with Atrial Fibrillation
… output. AF significantly elevates the risk of thromboembolic stroke, primarily due to thrombus formation in the left atrium (LA) and left atrial appendage (LAA). while electrophysiological mechanisms of AF are well defined, the LA structural and functional remodelling drives AF onset, …
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Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question
… filtration rate (GFR) is associated with thromboembolic and bleeding complications. Impaired kidney function has also been shown to be associated with a greater need of warfarin dose adjustment, poor TTR, and an increased risk of bleeding in patients taking warfarin. New anticoagulants, …
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Diethylstilbestrol Nanosuspensions for Prostate Cancer: Subcutaneous Sustained Release Formulations and Pre-clinical PK/PD Evaluations
… of its severe cardiovascular toxicity and thromboembolic complications such as deep vein thrombosis, pulmonary embolism and heart attack. At the same time, luteinizing hormone releasing hormone (LHRH) agonists were found to have similar efficacy profile to that of DES but with significantly …
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Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
… on patients with PPH and chronic large vessel thromboembolic pulmonary hypertension (TPH) seen at Groote Schuur Hospital between 1957 and 1985 in an attempt to: 1. Establish the diagnostic and prognostic value of clinical features, lung function tests, cardiac catheterisation, isotope lung …
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What is the efficacy of withholding perioperative anticoagulation bridging in patients with atrial fibrillation undergoing elective invasive procedures?
… in patients with AF, specifically focusing on thromboembolic events and bleeding incidents. Inclusion Criteria: This thesis details the conduct of a systematic review. We considered studies comparing adults aged eighteen and above diagnosed with AF and CHA2DS2-VASc score of one or more, …
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The prevalence, determinants, natural history and impact of atrial fibrillation and atrial flutter in patients with tuberculosis pericarditis - insights from the IMPI trial
… morbidity, as well as complications related to thromboembolic disease and haemodynamic instability. Similarly, atrial flutter (AFL) is a common macro-reentry arrhythmia, often associated with AF and its complications. While there is a recognized association between atrial fibrillation and / or …
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Signal Transduction and Gene Regulation in Cerebral Arteries Following Ischemia
… and protein regulation in human MCA following thromboembolic stroke so as validate previous findings in connection with experimental rat models. * Molecular characterization of smoke induced changes in cerebral arteries.
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Die Mikrodiagonalpumpe : tierexperimentelle Untersuchung eines Linksherzunterstützungssystems unter besonderer Berücksichtigung des Thromboembolie-Risikos
… of complications. Amongst others, bleeding and thromboembolic complications occur, which adversely affect the outcome of patients. The aim of this study was therefore to evaluate a new left ventricular assist device, developed from the Institute of Biomedical Science in Aachen, in an animal …
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A retrospective review of CTPA confirmed pulmonary emboli in COVID-19 patients admitted to Groote Schuur Hospital, Cape Town
Background: A high incidence of thromboembolic phenomena has been widely reported in patients with COVID-19 pneumonia. There is, however, a paucity of data detailing the incidence and characteristics of pulmonary emboli (PE) in COVID-19 patients in the South African setting. An improved …
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Die Rolle der Thrombozyten- und Leukozyten-Endothelzell-Interaktion in der Atherogenese
… - Platelets play a crucial role in thromboembolic complications of advanced atherosclerotic lesions but their involvement in the initiation of the atherosclerotic process in unclear. Platelet adhesion regulates secretion of intracellulary stored proinflammatory and proliferative …
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Störungen der Balance zwischen vasodilatativen und vasokonstriktiven Mediatoren während des extrakorporalen Kreislaufs bei Neugeborenen
… the renal function and for an amplification of thromboembolic events. These relations should be investigated more deeply in further studies. Summing up, longer times of extracorporeal perfusion and of aortic cross-clamping as well as the performance of a circulatory arrest, involved amplified …
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Die hämodynamische und klinische Funktion der Medtronic Mosaic Bioprothese in Aortenposition
… event rates at seven years were 96.8% ± 1.8% for thromboembolic events, 97.2% ± 2.0% for thrombosed bioprosthesis, 96.6% ± 2.6% for structural valve deterioration, 98.2% ± 1.8% for nonstructural dysfunction, 95.9% ± 2.0% for antithromboembolic hemorrhage, 98.9% ± 1.1% for endocarditis and 93.9 % ± …
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