Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"thrombin cleavage"”.
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Membrane binding properties of Disabled-2
… but not PIP2, protect Dab2 N-PTB from thrombin cleavage. By studying the mechanism by which Dab2 targets membranes, we will have the opportunity to manipulate its function in different lipid-dependent biological processes.
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Bmp proteins in urodele myotube cell cycle re-entry and in regeneration
… to serum. In particular, it was found that thrombin cleavage induces a factor in serum of all animals tested so far to promote S phase re-entry in A1 myotubes. We have used this S phase re-entry of the A1 cell line to purify the serum activity and developed a 5-step purification protocol …
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Characterisation of protease activated receptors
The thrombin receptor is a seven transmembrane G-protein-coupled receptor that is activated by thrombin cleavage. In order to characterise the thrombin receptor three mouse monoclonal antibodies were isolated by using a recombinant fusion protein incorporating the extracellular domain of the human …
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Thrombin-Inhibiting Perfluorocarbon Nanoparticles: A New Class of Therapeutic for Acute Thrombosis Treatment and Diagnosis
… that a nanoparticle carrying potent direct thrombin inhibitors can advance the treatment of acute thrombosis arising from various cardiovascular pathologies. The thrombin-inhibiting nanoparticles presented herein are designed to focus the antithrombotic impact of direct thrombin inhibitors …
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Studies on the Structure of Human Fibronectin
… plasma fibronectin was cleaved with human α-thrombin, and three major fragments were recovered: two large ones with molecular weights of approximately 230,000 and 235,000, and a small one with a molecular weight of 29,000. All three fragments appeared to consist of single polypeptide chains. …