Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 489 for “"threonine"”.
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Analysis of a bacterial serine/threonine kinase
RdoA is a bacterial protein kinase from Salmonella enterica serovar Typhimurium first noted for its regulation of dsbA expression in this organism. The crystal structure of RdoA’s homologue, YihE from Escherichia coli, revealed a basic bi-lobal kinase domain that is a hallmark of the eukaryotic …
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Threonine Phosphorylation Regulates Two-Component Systems Involved in Cell Wall Metabolism
… bacteria also contain eukaryotic-like serine/threonine kinases (eSTK). In the past decade these kinases and their partner eukaryotic-like phosphatases have been characterized. However, their in vivo substrates still remain largely unknown. My thesis project describes how eukaryotic-like …
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RhoA and Rac1 prenylation: Effects on serine/threonine signaling for actin polymerization
RhoA and Rac1 are small guanosine triphosphates (GTPases) that regulate cytoskeletal rearrangements, cell polarity and axon guidance and signaling pathways. Alteration of the subcellular localization or activation of Rho GTPases is implicated in several neurological conditions. Rho GTPases are …
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L-threonine : its ability to increase glycine mediated neurotransmission and suppress spasticity
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1989.
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Serine/threonine phosphorylation in mycobacterium tuberculosis : identification of protein kinase B (PknB) substrates
… bacterium is poorly understood. PknB is a serine/threonine kinase essential for the in vitro survival of M. tuberculosis and therefore a potential drug target against the bacteria. It is the goal of the current study to elucidate downstream substrates of PknB. We have found that PknB shares in …
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Functional analysis of syp1, a novel substrate of the serine/threonine kinase prk1
In budding yeast, the actin and septin cytoskeletons are important for the establishment of cell polarity. During the cell cycle, these cytoskeletons undergo dramatic reorganization which is regulated by many cytoskeleton-associated proteins. In this study, Syp1p has been found to have functional …
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Characteristics of threonine, valine and methionine absorption in the jejunum and ileum of sheep
… used to study the absorption characteristics of threonine, valine and methionine. Perfusions of the cannulated intestine were conducted 4 hr after feeding for a 1 hr period. Absorption of amino acids was measured as the total amount of amino acid removed from the perfusion solution during the 1 …
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Growth of Thoroughbreds fed Different Levels of Protein and Supplemented with Lysine and Threonine
… fiber, and was fortified with .6% lysine and .4% threonine. Lysine and threonine are the first two limiting amino acids in common diets of the horse. Mares and foals were fed twice daily (0700 and 1400) and kept on 30-acre pastures (mixed grass/white clover) until weaning (7 months). Weanlings …
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In vitro absorption of valine, threonine and methionine by the small intestine of sheep
… to study <i>in vitro</i> absorption of valine, threonine and methionine. Everted sacs were incubated for 45 minutes at 39 C under an atmosphere of 95% O₂ - 5% CO₂ in Krebs-Ringer bicarbonate buffer (mucosal and serosal fluid) containing 5 μmoles per ml of the test amino acid. The hydrolyzed …
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Characteristics of threonine, valine and methionine absorption in the jejunum and ileum of sheep
… used to study the absorption characteristics of threonine, valine and methionine. Perfusions of the cannulated intestine were conducted 4 hr after feeding for a 1 hr period. Absorption of amino acids was measured as the total amount of amino acid removed from the perfusion solution during the 1 …
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Dietary guanidino acetic acid spares arginine and dietary l-homoserine spares threonine in the chick
Guanidino acetic acid (GAA) is synthesized in the liver and kidney from Arg and Gly. It is subsequently methyllated by S-adenosylmethione to creatine. L-Homoserine (HS) has been identified as an intermediate compound in the metabolism of Thr, Met, and Asp. Bacteria, plants and yeast can synthesize …
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Studies into the role of capsid serine/threonine residues in HIV core stability and virus replication.
Disassembly of the HIV viral core describes the rearrangement and release of capsid (CA) from the core following entry into the host cell. In this process, while the conical shaped core may be lost, some CA remains associated with the resulting reverse transcription (RTC) and preintegration …
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A Genetic and Biochemical Analysis of Attenuation Regulation in the Threonine Operon of Escherichia Coli-K12
Threonine biosynthesis in Escherichia coli K-12 was proposed to be regulated by an attenuation mechanism. A genetic and biochemical analysis was performed to provide more evidence that attenuation was the mechanism utilized to regulate threonine biosynthesis.
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