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Showing 1 to 1 of 1 for “"thiolactone macrocycle"”.
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Studies on the Maturation of Secreted Quorum Sensing Peptides That Regulates S. Aureus Virulence
… the role of AgrB in secreting the AgrD(1-32)-thiolactone and 2) confirm that SpsB is the protease responsible for the final cleavage step of AgrD in AIP biosynthesis. To achieve these goals, an in vivo secretion assay using intein chemistry to produce AIP in the absence of AgrB was developed …