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Showing 1 to 3 of 3 for “"thiol-Michael addition"”.

  1. Design and Synthesis of Cellulose Ether Derivatives for Oral Drug Delivery

    … post-CM hydrogenation and then explored a thiol-Michael addition to the α,β-unsaturation, which also incorporates an extra functional group through the thioether. We have successfully prepared a collection of cellulose 𝜔-carboxyether derivatives through the above-mentioned method and …

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  2. Development of an Injectable Hydrogel Platform to Capture and Eradicate Glioblastoma Cells with Chemical and Physical Stimuli

    … referred to as glioma stem cells (GSCs). Additionally, the migratory nature of GBM/GSCs enable them to invade into the healthy brain parenchyma beyond the resection cavity to generate new tumors. In an effort to address these challenges of GBM recurrence, this research aimed to develop a …

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  3. Chemical Modification of Cellulose Esters for Oral Drug Delivery

    … of these reactive conjugated olefins by post-CM thiol-Michael addition. Under amine catalysis, different CM products and thiols were combined and reacted. Using proper thiols and catalyst, complete conversion can be achieved under mild reaction conditions. The combination of the two modular …

    vt Repository record for Chemical Modification of Cellulose Esters for Oral Drug Delivery (opens in a new tab)