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Showing 1 to 1 of 1 for “"thermorubin"”.
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Operation Hot Sandwich: Incorporating pyrones in [4 + 2] cycloaddition reactions to prepare thermorubin
… leads for future drugs. One such metabolite is thermorubin, a molecule with a unique scaffold and bacteriostatic mechanism of action. It shows promising sub micromolar activity against both Gram-positive and negative bacteria but suffers from poor oral bioavailability. Difficulties in obtaining …