Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"thermal dose"”.
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Determination of Thermal Dose Model Parameters Using Magnetic Resonance Imaging
… monitoring temperature during minimally invasive thermal therapy procedures. When coupled with thermal dose models, MRTI feedback provides the clinician with a real-time estimate of tissue damage by functioning as a surrogate for post-treatment verification imaging. This aids in maximizing the …
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Optimal Control of Thermal Damage to Biological Materials
… protocol that will cause a desired amount of thermal damage within a region of tissue. The optimization algorithm is validated experimentally on an albumen tissue phantom. The transient temperature distribution within the region is simulated using a two-dimensional, finite-difference model of …
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Feasibility of a predictive model of Hsp70b-activated gene therapy protein expression during ultrasound hyperthermia
… total Hsp70b mRNA production generated by thermal shock and thermal dose, a predictor of dose often used in hyperthermia therapies. The relationship found between total Hsp70b mRNA production and thermal dose suggests that a real-time predictive model of therapeutic protein dose kinetics …
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Theoretical Feasibility Study of Preferential Hyperthermia Using Silicon Carbide Inserts
… heating could be used to attain the desired thermal dose (DTD) for a two cm diameter tumor. The simulations in this work show that, when using a single silicon carbide insert, the model cannot provide enough energy for an entire 2 cm diameter tumor to receive the DTD. However, when using an …
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Development of MR Thermometry Strategies for Hyperthermia of Extremity and Breast Tumors
… temperature highlights the need for accurate thermal dosimetry, so that the prescribed thermal dose can be delivered to the tumor. This can be achieved noninvasively with MR thermometry. However, there are many challenges to performing MR thermometry in the breast, where hyperthermia of …
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Engineering Considerations for Treatment of Prosthetic Joint Infections Using Alternating Magnetic Fields (AMF)
… predicted 2-3 mm of tissue damage using a CEM43 thermal dose model for 1-h AMF exposures targeting 65°C for pulse delays of 2.5 and 5 mins. This study confirmed that AMF technology can be scaled up to treat implants in a large animal model with the same rates of heating and peak temperature as …
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Development of Feedback Microwave Thermotherapy in Symptomatic Benign Prostatic Hyperplasia.
… for helping the doctor to tailor the individual ?thermal dose? to each patient. The clinical efficacy, 1 and 5 years after PLFT and Trans-urethral Resection of the Prostate (TURP), is compared showing no statistically significant differences. Serious adverse events were more frequent after TURP. …
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Non-invasive in vivo ultrasound temperature estimation
New emerging technologies in thermal therapy require precise monitoring and control of the delivered thermal dose in a variety of situations. The therapeutic temperature changes in target tissues range from few degrees for releasing chemotherapy drugs encapsulated in the thermosensitive liposomes …