Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"therapy-related myeloid neoplasms"”.
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Spectrum and Incidence of Primary and Therapy-Related Hematologic Malignancies In Individuals With Brca1 and Brca2 Pathogenic Variants
<p>Therapy-related myeloid neoplasms (t-MN) are rare and deadly hematologic malignancies that develop following exposure to cytotoxic therapies such as radiation, chemotherapy, and poly (adenosine diphosphate-ribose)-ADP polymerase (PARP) inhibitors. Preliminary evidence suggests that germline …
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EVALUATION OF THE RISK OF SECONDARY LEUKEMIAS IN CANCER SURVIVORS
Therapy-related myeloid neoplasms (t-MNs) are severe late complications of chemotherapy and/or radiotherapy in cancer survivors, characterized by dismal prognosis and resistance to treatment. Chemotherapy may also play a role in increasing clonal hematopoiesis (CH), a clinical entity associated …