Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 337 for “"therapeutic interventions"”.
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Preclinical translation of therapeutic interventions for tendon injury
… economy is significant. Unfortunately, current therapeutic interventions have high re-injury rates and do not restore the optimized multiscale structure and function of the healthy tendon or attachment. Investigations are needed to further develop and validate methods to prevent re-injury and …
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The Pathophysiological Mechanisms of Alzheimer's Disease; Investigating Therapeutic Interventions for Disease Onset
… disease development is vital to help design new therapeutic interventions beyond amyloid alone. Presented here are a collection of mechanisms uncovered that likely play into the development of Alzheimer’s Disease and pose potential new routes for therapies to improve patient outcomes. Here we …
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Νέες θεραπευτικές παρεμβάσεις στην HIV λοίμωξη / New therapeutic interventions in HIV infection
Η HIV λοίμωξη (Ιός Ανθρώπινης Ανοσοανεπάρκειας) παραμένει μια από τις πιο σοβαρές παγκόσμιες προκλήσεις στον τομέα της Δημόσιας Υγείας. Η παρούσα διπλωματική εργασία έχει ως σκοπό να αναλύσει κάποιες από τις σύγχρονες θεραπευτικές προσεγγίσεις, αλλά και τις προκλήσεις που σχετίζονται με τη …
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Neurological Consequences of Viral Encephalitis: Behavioral Deficits, Neuronal Restructuring, and Therapeutic Interventions
… of broad-spectrum antiviral and neuroprotective therapeutics. First, we investigate the acute and chronic neurological consequences of VEEV infection using a murine model, focusing on behavioral, neuropathological, and transcriptomic changes. Mice displayed decreased anxiety-like behavior, …
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Epicardial Adipose Tissue: Relationship with Cardiovascular Disease and the Effect of Therapeutic Interventions
Background <br/>Until recently, research has been directed towards the intra-abdominal visceral fat and its relationship with metabolic syndrome and the role of inflammatory mediators. However, recent research has shown that mediastinal visceral fat and, in particular, epicardial adipose tissue …
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Ampa Receptor Dysregulation And Therapeutic Interventions In A Mouse Model Of Cdkl5 Deficiency Disorder
… synapses. Finally, we evaluated the therapeutic potential of GluA2-lacking AMPAR blocker IEM-1460 as well as cannabidiol to observe 1) whether blocking increased hippocampal GluA2-lacking AMPARs would attenuate behavioral alterations and hyperexcitability in R59X mice and 2) whether …
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Non-Traditional Therapeutic Interventions for At-Risk Youth & Students with Complex Support Needs: Equine Therapy
The increased need for effective interventions and the challenge of working with children and youth with complex support or at-risk needs such as emotional disorders, physical and mental health needs as well as autism; have resulted in the design of many non-traditional therapeutic interventions, …
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Preventing type 2 diabetes microvascular complications: Exploring the interplay of racial/ethnic disparities and primary therapeutic interventions
… are often prescribed to treat T2DM. These T2DM interventions may lower risk of microvascular complications over time; however, findings from clinical and epidemiologic studies have been inconsistent. Furthermore, the effects of these interventions on risk may vary by race/ethnicity, but …
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Healing beyond the scars of female genital mutilation (FGM): the experiences of Somali women in England with therapeutic interventions
This thesis explores the therapeutic experiences of Somali women in the UK who have undergone Female Genital Mutilation (FGM) or FGM reversal. It focuses on participants' perceptions of psychological interventions and, from these experiences, assesses the cultural competence of therapeutic …
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Exploring therapists’ experiences of using therapeutic interventions from Muslim perspectives for Muslim clients: Usefulness, contribution and challenges in the UK.
… a need for making use of models, techniques and therapeutic interventions based on Muslim perspectives for Muslim clients has repeatedly been expressed (Haque, 2004a; Helms, 2015; Inayat, 2007; Keshavarzi & Haque, 2013; Utz, 2012; Weatherhead & Daiches, 2010). Despite recommendations for using …
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A Review of Associations Between Traumatic Brain Injury & Addiction and Therapeutic Interventions for Addiction in the Brain Injured Population
The research linking drug and alcohol use with increased risk of sustaining a traumatic brain injury (TBI) has been well established. There is some evidence suggesting that the inverse relationship exists; that sustaining a TBI increases the likelihood for developing a drug or alcohol abuse …
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Molecular regulation of the cardiac-enriched acetyl-CoA carboxylase isoform (ACCβ) : a novel target for therapeutic interventions in cardiovascular disease
… initiative toward the development of novel therapeutic interventions. To further investigate the role of metabolic substrate switches in the heart, we focused on a pivotal, rate-limiting step of cardiac fatty acid metabolism i.e. an upstream modulator of long-chain fatty acid importation …
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Study of the impact of abuse on children, adult survivors and practioners, and the implications for service delivery and therapeutic interventions.
… and on the implications for service delivery and therapeutic interventions. I consider how practice has fed and focussed my thinking on areas subsequently studied, explored and described in these publications; and that these are fundamentally deeply rooted in and with survivors, but significantly …
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Exploring the language of adolescent emotion and its relationship with psychological wellbeing and therapeutic experience
… language use and production within UK adolescent therapeutic populations has received relatively little attention compared to other client-, process- and outcome factor research. In recent years, novel and distinct methods of delivering therapy that rely on the production and interpretation of …
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Informed consent and the secondary use of biospecimens in oncology research legal and bioethics perspectives
… collected during routine oncology diagnostic and therapeutic interventions may be stored for future medical purposes. In accordance with legal and ethical principles, the patient provides informed consent for removal of the tissue for diagnostic or therapeutic reasons. Informed consent gives …
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Psychotherapy for sequelae of trauma based on testimonies of victims at the Truth and Reconciliation Commission
… the results themes in symptoms systems and psychotherapeutic interventions were also derived. These themes included physical and psychological symptoms, macro- contextual systems and therapeutic interventions. Systems theory proved useful in historically understanding symptoms within the context …
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Psychotherapeutic interventions for clients seeking long-term romantic relationships, yet displaying intimacy avoidance patterns: a thematic analysis of clinicians' experiences
… study is a qualitative investigation into what therapeutic interventions psychological practitioners employ when they encounter clients who experience avoidance attachment patterns in dating and relationship formation. Taking a point of departure in attachment theory the paper considers how …
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The Relationship between College Students’ Purpose in Life and Risk-Taking Behavior
… as well as directions for future research and therapeutic interventions are discussed.
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Novel insights into the inflammatory basis of gastrointestinal disease
… information on these disorders and improve the therapeutic interventions available in these debilitating conditions. I will assess the role of inflammation in disorders of the GI tract and liver IBD, IBS, hepatic inflammatory injury and furthermore, I will use pharmaceutical agents to activate …
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