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Showing 1 to 3 of 3 for “"theoretical immunology"”.

  1. Optimization of influenza vaccine strain selection

    … In this work, we use recent results from theoretical immunology to formulate the vaccine selection problem as a discrete-time stochastic dynamic program with a high-dimensional continuous state space. We discuss the techniques that were developed for solving this difficult dynamic program, …

    mit Repository record for Optimization of influenza vaccine strain selection (opens in a new tab)

  2. Mathematical Models of Immune Responses to Infectious Diseases

    In this dissertation, we investigate the mechanisms behind diseases and the immune responses required for successful disease resolution in three projects: i) A study of HIV and HPV co-infection, ii) A germinal center dynamics model, iii) A study of monoclonal antibody therapy. We predict that the …

    vt Repository record for Mathematical Models of Immune Responses to Infectious Diseases (opens in a new tab)

  3. Mathematical models of immune responses during external challenges and autoimmunity

    Characterizing the mechanisms of the immune system and its response to infection and autoimmunity is crucial for understanding and predicting disease outcomes and evaluating potential interventions at multiple scales. While data provide a snapshot of certain biological phenomena, they cannot …

    vt Repository record for Mathematical models of immune responses during external challenges and autoimmunity (opens in a new tab)