Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"tendon regeneration"”.
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Mesenchymal Stem Cell Mechanobiology and Tendon Regeneration
Tendon function is essential for quality of life, yet the pathogenesis and healing of tendinopathy remains poorly understood compared to other musculoskeletal disorders. The aim of regenerative medicine is to replace traditional tissue and organ transplantation by harnessing the developmental …
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Adipose-Derived Adult Stem Cells as Trophic Mediators of Tendon Regeneration
… is a promising new therapy for equine flexor tendonitis. This heterogeneous population of cells may improve tendon healing via the production of growth and chemotactic factors capable of recruiting endogenous stem cells and increasing extracellular matrix production by tendon fibroblasts …
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Tendon Regeneration: Roles of Growth Factors and Phenotypic Diversity in Tendon Stem Cells
Tendon injuries significantly impact quality of life and are often career ending. Mesenchymal stem cell (MSC) therapy is known to augment intrinsic tendon healing, however, little is known of the stem cells endogenous to tendon, the microenvironmental cues that induce tendon differentiation, and …
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Characterising embryonic stem cell-derived tenocytes and determining the changing role of scleraxis during tendon development
Tendon injuries occur commonly in equine athletes. Adult tendons undergo poor natural regeneration, resulting in scar-tissue which is prone to re-injury. Fetal tendons however are capable of completely scar-less regeneration, a property which is intrinsic to the fetal cells themselves. Novel cell …
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Engineering cellular microenvironments for directed cell growth and migration
… health (1) using micropatterned surfaces for tendon regeneration, and (2) using microfluidic platforms for neutrophil chemotaxis. Both of these applications are of crucial importance in modern biological and medical advancement. We have developed micropatterned platforms for systematic …
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Enhancement of spatially-controlled MSC responses in a multi-compartment CG scaffold for tendon-bone junction regeneration
… field of tissue engineering for the repair or regeneration of single tissues. However, orthopedic injuries often occur at the interface between soft tissues and bone. The tendon-bone junction (TBJ) is a classic example of such an interface, containing overlapping patterns of growth factors, …