Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 142 for “"temporal lobe"”.
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Temporal Lobe Transients and Prayer
… originate in the limbic system and affect the temporal lobes of the brain. According to this theory, ritual behavior could be used by individuals to induce micro-seizure activity. The theory predicted that an increase in alpha and theta activity in the temporal lobes of the brain would occur …
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Medial Temporal Lobe Structure and Function
Medial Temporal Lobe Structure and Function by Meghana Sunil Karnik Doctor of Philosophy in Biology and Biomedical Sciences: Neuroscience) Washington University in St. Louis, 2009 Professor John G. Csernansky, Chairperson My main goal was to examine the relationship between brain structure and …
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Content representation in the human medial temporal lobe
… surprise? It is well-established that the medial temporal lobe (MTL) is crucial to both processes, but the MTL is not a single homogeneous region. In fact, it is composed of several anatomically distinct subregions including hippocampus, perirhinal cortex (PRC) and parahippocampal cortex (PHC). …
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Medial Temporal Lobe Structures Contribute to on -Line Processing
… the emerging view that structures of the medial temporal lobe contribute to the on-line processing of visual stimuli. These experiments uniquely demonstrate that the MTL is necessary for normal apprehension of even single stimuli when degraded, and for normal discrimination of even very simple …
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HORROR-EVOKED AROUSAL AND AMYGDALA BIAS OF THE MEDIAL TEMPORAL LOBE
… arousal either enhances or disrupts temporal order memory (Cliver et al., 2024; Gregory & Murty, n.d.). In both behavioral (Study 1 and Study 2) and neuroimaging (Study 2) analyses to investigate the relationship between threat-related neural circuitry during encoding of short movie …
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Visual perception and memory after anterior temporal-lobe lesions in humans
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1996.
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Memory Performance in Children with Temporal Lobe Epilepsy: Neocortical vs. Dual Pathologies
This study investigated memory in children with temporal lobe epilepsy and the ability to discern hippocampal dysfunction with conventional memory tests that are typically used to detect more global memory impairment. All data was obtained retrospectively from the epilepsy surgery program at a …
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Respiratory Biomarkers in Kv1.1 Knockout Mice, a Model for Temporal Lobe Epilepsy
… in Kv1.1 knockout (KO) mice, a model of temporal lobe epilepsy and SUDEP. We reported respiratory abnormalities in KO mice using the methacholine (MCh) challenge, indicating that increased breathing rate, apnea and respiratory failure is associated with SUDEP. We have also found that the …
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Quantitative MRI correlates of hippocampal and neocortical pathology in intractable temporal lobe epilepsy
… steps whereby sparsely sectioned histology from temporal lobe specimens was first registered to the intermediate ex-vivo MRI which is then registered to the in-vivo MRI, completing a pipeline for histology to in-vivo MRI registration. When correlating relaxometry and DTI with neuronal density and …
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The Effects of Smoking on Neuropsychological Functioning Among Patients with Temporal Lobe Epilepsy
… of chronic cigarette smoking in patients with temporal lobe epilepsy (TLE). Smoking is important to study in this population because cognitive profiles are relied on extensively for treatment planning, and thus the discrimination of smoking-related cognitive patterns from those secondary to …
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Medial temporal lobe and prefrontal cortex contributions to memory expressed on short timescales
… adaptive behavior in the moment. The medial temporal lobe (MTL) is critical for human memory. Its role in memory at long delays is well-established, while its contribution to memory at short delays had not been appreciated until recently, when studies specifically targeted the kind of …
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Beyond Episodic Memory: Medial Temporal Lobe Contributions to Problem-solving and Semantic Fluency Tasks
… memory processes supported by the medial temporal lobes (MTL) to two goal-oriented non-episodic tasks, problem solving and semantic retrieval (verbal fluency). The reported experiments provide evidence for the hypothesis that MTL-based episodic processes are robustly involved in completing …
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Disambiguating the Similar: Investigating Pattern Separation in Medial Temporal Lobe Structures Using Rodent Models
This dissertation investigates the mechanisms underlying pattern separation, using rodent models and behavioural tasks that assess the use of representations for similar stimuli. Pattern separation is a theoretical mechanism involving the transformation of inputs into output representations that …
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Neuropsychological Profiles in Temporal Lobe Epilepsy With and Without a History of Traumatic Brain Injury
… deficits have long been observed in those with temporal lobe epilepsy (TLE). Language and verbal memory are often impaired in individuals with left TLE and visuospatial and visual memory can be impaired in patients with right TLE. Traumatic brain injury (TBI) is the most common known cause of …
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Characterizing Medial Temporal Lobe Neurodegeneration Due To Tau Pathology In Alzheimer's Disease Using Postmortem Imaging
… tangle (NFT) pathology in the medial temporal lobe (MTL) is closely linked to neurodegeneration, and is the early pathological change associated with Alzheimer’s Disease (AD). Using in vivo structural magnetic resonance image (MRI) analysis, volumetric change in the MTL caused by …
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Cognitive neuroscience methodologies provide insight into medial temporal lobe contributions to perception, language, and creativity
The functional contribution of medial temporal lobe has been studied in the human brain for over half a century. Insight into the nature of this extraordinary structure was discovered when epileptic patient H.M. had an experimental operation to surgically resect his bilateral medial temporal lobes. …
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ANATOMICAL AND ELECTROPHYSIOLOGICAL STUDIES OF AN ANIMAL MODEL OF TEMPORAL LOBE EPILEPSY WITH CLASSIC HIPPOCAMPAL SCLEROSIS
In mesial temporal lobe epilepsy, seizures often arise from an atrophic hippocampus exhibiting a characteristic pattern of hippocampal neuron loss called "classic hippocampal sclerosis." No single injury has reproduced this extensive neuron loss experimentally, suggesting that hippocampal sclerosis …
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