Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 68 for “"temporal expression"”.
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Temporal Expression and Transcriptional Regulation of the Vitellogenin Receptor Gene In Largemouth Bass (Micropterus Salmoides)
<p>Fish vitellogenin (VTG) synthesized and released from the liver of oviparous animals is taken up into oocytes, in part, by the vitellogenin receptor (VtgR). Some studies have focused on the functional role of VtgR in fish; however the transcriptional control of this gene has not been …
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Temporal Processing of News: Annotation of Temporal Expressions, Verbal Events and Temporal Relations
The ability to capture the temporal dimension of a natural language text is essential to many natural language processing applications, such as Question Answering, Automatic Summarisation, and Information Retrieval. Temporal processing is a ¯eld of Computational Linguistics which aims to access …
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Immunological and Molecular Analyses of the Borrelia burgdorferi OspF Protein Family F
… human infection. Immunoblot analyses revealed a temporal expression of OspF proteins during infection and mapped the immunodominant epitopes which lie within the variable domains. To determine if OspF-related proteins are produced by other isolates, immunoblot analyses were performed using sera …
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Part I characterization of MyoR in C2C12 mouse fibroblasts. Part II isolation and characterization of a novel class II bHLH transcription factor from the black widow spider, latrodectus hesperus
… and muscle cell differentiation, we analyzed the temporal expression at both the mRNA and protein level. Unlike previous studies, we have utilized reverse transcriptase quantitative PCR to analyze mRNA expression. This allows quantitative analysis of MyoR mRNA levels during muscle cell …
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Towards functional assignment of Plasmodium membrane transport proteins: an experimental genetics study on four diverse proteins
… four selected Plasmodium MTPs, including spatio-temporal expression and phenotypical analysis of knockout mutants. We employed the murine malaria model parasite Plasmodium berghei and in vitro blood cultures of the human malaria parasite Plasmodium falciparum. For this study, we selected one …
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Towards functional assignment of Plasmodium membrane transport proteins: an experimental genetics study on four diverse proteins
… four selected Plasmodium MTPs, including spatio-temporal expression and phenotypical analysis of knockout mutants. We employed the murine malaria model parasite Plasmodium berghei and in vitro blood cultures of the human malaria parasite Plasmodium falciparum. For this study, we selected one …
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Expresso-AI : a framework for explainable video based deep learning models through gestures and expressions
… saliency maps by analyzing face regions and temporal expression semantics. Our framework generates both visual and quantitative explanations on the model's decision. Simultaneously, our video based modeling has improved previous single-face benchmarks of visual Automatic Depression Detection …
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Regulation of Cyclin G2 Degradation in Human Ovarian Cancer Cells
… Normal cell cycle progression is governed by temporal expression of canonical cyclin molecules, which then bind to and activate CDKs. Cyclin G2, an unconventional cyclin, negatively regulates cell cycle and its levels are lowered in various types of cancer. Our lab has previously reported that …
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Characterization of CPG15 during cortical development and activity dependent plasticity
… Using in situ hybridization, we monitored cgp15 expression in 4-week-old mouse barrel cortex after trimming all whiskers except D1. We found that cpgl5 expression is depressed in the deprived barrels and enhanced in the barrel column corresponding to the spared D1 whisker. Induction of cpgl5 …
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Functional characterization and analysis of Carica papaya SHORT VEGETATIVE PHASE (CpSVP)
… time. In Arabidopsis, we studied the spatial and temporal expression of CpSVP during vegetative and reproductive stages. CpSVP-Y and CpSVP-Yh are expressed transcriptionally in the floral organs, pedicels and leaves under its native 2kb promoter regulation but only CpSVP-Y allele can cause pedicel …
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Chondrocyte gene expression and intracellular signaling pathways in cartilage mechanotransduction
… 24 hours, we used real-time PCR to measure the temporal expression profiles of selected genes associated with cartilage homeostasis. In concurrent experiments, we assessed the involvement of intracellular signaling pathways using molecular inhibitors. In order to interpret the results we …
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Comparative analysis of the promoters of the CyI-CyIIa-CyIIb actin gene cluster in the sea urchin Strongylocentrotus purpuratus
… similar proteins. However, their spatial and temporal expression patterns are differentially regulated. The region of CyIIa upstream of the ATG and putative transcription start site was subcloned and sequenced. Sites of protein-DNA interaction were identified using DNaseI footprinting. …
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Polyamine metabolism in Arabidopsis: Transgenic manipulation and gene expression
… techniques of transgenic manipulation and gene expression. Two specific objectives were: (1) To study the effects of inducible and constitutive transgenic manipulation of polyamines via a mouse ornithine decarboxylase (mODC) gene on plant metabolism. (2) To analyze the spatial and temporal …
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Using machine learning to predict gene expression and discover sequence motifs
… to discover gene sequence motifs associated with temporal expression patterns of genes. Our algorithm, which is based on partial least squares (PLS) regression, is able to directly model the flow of information, from gene sequence to gene expression, to learn cis regulatory motifs and characterize …
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Biosynthesis and Signaling of Glucocorticoids and Progestins and Their Effects on Myelin Synthesis in Schwann Cell/neuronal Co-Cultures
… manner. Both steroids increased the expression levels of myelin glycoprotein Po and the number of myelin internodes in treated co-cultures. It was discovered that Schwann cell/neuronal co-cultures synthesize many different steroids. When [7-3H] pregnenolone and [1,2-3H] …
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Role of PI3K and MAPK in Regulating the IL-10-Induced Temporal Transcriptional Program in LPS-Triggered Macrophages
… the cytokine interleukin-10 (IL-10) induces expression of a set of anti-inflammatory genes that act to inhibit expression of TLR-induced pro-inflammatory genes. While many of the IL-10-induced genes can be induced by IL-10 stimulation alone, some others, such as TNIP3, are only …
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Understanding the functional consequences of genetic variation on gene regulation
… non-coding sequence of the genome and the gene expression is one of fundamental goals of regulatory genomics. Perturbing certain locations in the non-coding DNA causes a disturbance to the precise spatial and temporal expression of the genes. Gene regulatory mechanisms determine the amount of …
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Pax3 expression in cutaneous malignant melanoma
… the repercussions of aberrant PAX3 re-expression in cutaneous malignant melanoma (CMM). The transcription, factor encoded by PAX is amongst the first expressed in the embryo, with a principal role in the development of the melanocytic lineage. We theorised that abnormal re-expression of …
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Predicting genetic interactions in Caenorhabditis elegans using machine learning
… they have similar development and aging temporal expression profiles. One of the major difficulties in dealing with biological data is the problem of incomplete datasets. We describe a novel application of collaborative filtering (CF) in order to predict missing values in the biological …
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A molecular-genetic study of Congenital Nystagmus
… culture and RT-PCR work is performed to study expression of this gene. Additionally a pedigree with an atypical congenital nystagmus disorder is investigated and a new mutation within a known cerebellar disease gene is identified.<br/>This work contributed to the identification of the first …
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