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Showing 1 to 1 of 1 for “"telomerase, BRCA1, breast cancer, telomeres"”.

  1. Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells

    … An increasing body of evidence suggests BRCA1, a tumor suppressor gene with a variety of functions including DNA repair and cell cycle regulation, plays a role in telomere maintenance. Mutations in BRCA1 account for approximately half of all hereditary breast and ovarian cancers, and the …

    iupui Repository record for Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells (opens in a new tab)