Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"targeted release"”.
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TUMOR-TARGETED RELEASE OF IMMUNOSTIMULATORY AGENTS: SYNTHESIS AND BIOLOGICAL EVALUATION OF IMIDAZOQUINOLINE-BASED PRODRUGS AND ANTIBODY CONJUGATES
… have been proposed in order to achieve the targeted delivery of anticancer agents at the tumor site. Amongst the different delivery vehicles proposed, antibody drug conjugates (ADCs) have been especially successful in the clinic. Recently, the involvement of the immune system in cancer …
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Encapsulation of chemical catalyst and structural epoxy in microcapsules generated via microcapillary devices
<p>Protection and controlled release of chemicals through encapsulation have been extensively used in daily applications such as drug delivery, food processing, enzyme stabilization, and chemical storage. A significant need for further development in this area is to reduce the capsule size and to …
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Layer-by-Layer Systems for Craniomaxillofacial Bone Repair
… It is becoming increasingly recognized that release rate of growth factor proteins signaling bone regeneration and vascularization is a key optimization parameter since these proteins are rapidly cleared from the body and can have safety ramifications when released too rapidly. A clear …
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Environmental impact of stocked Mulloway (Argyrosomus japonicus) in New South Wales estuaries
… movements (greater than 10 km in 3 d) when released in shallow water, compared to hatchery-reared fish released directly over deep holes. Such targeted release strategies could revolutionise stocking of depleted fisheries in estuarine and aquatic habitats, and even oceans. Stomach content …
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Design and development of polymeric nanoparticles by continuous manufacture using twin screw extrusion
… the nanoparticles can allow for controlled or targeted release based on the polymer selection. Further studies will focus on implementing this design to develop other nanoparticle systems and further in vivo analysis.
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Bioaccessibility and metabolism of anthocyanins: effects of fermentation, encapsulation, and microbiota interactions
… investigated, increasing bioaccessibility and targeted release of anthocyanins to the colon. The in vitro metabolism of anthocyanins and SCFA production were analyzed in individuals with different body mass index (BMI) values. It was observed that the microbiota metabolized 37.45–54.01% of C3G …
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Single-Payload Bioconjugation to Native Antibodies And A General Method for the Self-Immolative Release of Amide-Containing Molecules
… (ADCs) have emerged as a powerful form of targeted cancer therapy that can deliver drugs with a high level of selectivity towards a specific cell type, reducing off-target effects and increasing the therapeutic window compared to small molecule therapeutics. However, creating ADCs that are …
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Microencapsulation of tributyrin to improve sensory qualities and intestinal delivery
… 3) determine the site of intestinal delivery and release of butyrate from microencapsulated TB, and 4) determine the sensory properties of food products containing microencapsulated TB. Microencapsulated TB in whey protein isolate (WPI)-based microcapsules resulted in higher (p<0.001) retention …